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Imaging of Myocardial Amyloid Involvement with 99m — Tc Aprotinin

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Radioactive Isotopes in Clinical Medicine and Research

Part of the book series: Advances in Pharmacological Sciences ((APS))

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Summary

We report on the use of 99m Tc-Aprotinin in the detection of myocardial amyloid involvement in a population of 45 pts with amyloidosis and 22 control subjects with renal and cardiac disease. Positive scans were obtained in 19 pts, no cardiac uptake was observed in the remaining 25 and in the controls. These results,confirmed by histology in 4 pts and by clinical-instrumental follow-up in 38, indicate TcA as a low-cost readily available tracer for cardiac amyloidosis detection.

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Authors and Affiliations

  1. Fondazione S.Maugeri, IRCCS- Nuclear Med. Serv, Pavia, Italy

    C. Aprile, M. G. Marinone, R. Saponaro, G. Cannizzaro, G. Calsamiglia, E. Anesi & G. Merlini

  2. Policlinico S.Matteo, IRCCS-Inst. of Clinical Med. II and Research Lab. Biotechnology, Pavia, Italy

    C. Aprile, M. G. Marinone, R. Saponaro, G. Cannizzaro, G. Calsamiglia, E. Anesi & G. Merlini

Authors
  1. C. Aprile
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  2. M. G. Marinone
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  3. R. Saponaro
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  4. G. Cannizzaro
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  5. G. Calsamiglia
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  6. E. Anesi
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  7. G. Merlini
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Editor information

Editors and Affiliations

  1. Allgemeines Krankenhaus Wien, Institut für Biomedizinische Technik und Physik, Währinger Gürtel 18-20, A-1090, Wien, Austria

    H. Bergmann

  2. Nuklearmedizinisches Institut, KA Rudolfstiftung, Juchg. 25, A-1030, Wien, Austria

    A. Kroiss

  3. Allgemeines Krankenhaus Wien, Universitäts-Klinik für Nuklearmedizin, Währinger Gürtel 18-20, A-1090, Wien, Austria

    H. Sinzinger

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© 1997 Springer Basel AG

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Aprile, C. et al. (1997). Imaging of Myocardial Amyloid Involvement with 99m — Tc Aprotinin. In: Bergmann, H., Kroiss, A., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7772-5_28

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  • DOI: https://doi.org/10.1007/978-3-0348-7772-5_28

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7774-9

  • Online ISBN: 978-3-0348-7772-5

  • eBook Packages: Springer Book Archive

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