Summary
We performed Tc99m-ECD interictal SPET in 26 children with severe therapy-resistant epilepsy. All children underwent detailed clinical examination, EEG investigation and brain MRI. In 21/26 children, SPET demonstrated brain blood flow abnormalities, 13 of them in the same territories with EEG alterations. MRI showed structural lesions in 6/26 children. These data confirm that brain SPET is considerably sensitive in detecting and localizing hypoperfused areas that could be associated with epileptic foci in these patients, even when the MRI pattern is normal.
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© 1997 Springer Basel AG
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Vattimo, A., Burroni, L., Bertelli, P., Volterrani, D., Vella, A. (1997). Tc99m-ECD Brain SPET in Diagnosis of Cerebral Perfusion Abnormalities in Children with Therapy-Resistant Epilepsy. In: Bergmann, H., Kroiss, A., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7772-5_18
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DOI: https://doi.org/10.1007/978-3-0348-7772-5_18
Publisher Name: Birkhäuser, Basel
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