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Actin and Thin-Filament-Associated Proteins in Smooth Muscle

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Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation

Part of the book series: Respiratory Pharmacology and Pharmacotherapy ((RPP))

Abstract

Actin is a major component of both contractile and cytoskeletal structures in all eukaryotic cells [1–4]. It can exist either as a monomeric molecule (G-actin) or as a filamentous polymer (F-actin). Both forms can be reversibly transformed one into another depending on ionic conditions, temperature and the presence of other proteins. The only functional form of actin is F-actin.

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  1. Department of Muscle Biochemistry, Nencki Institute of Experimental Biology, Warsaw, Poland

    Renata Dąbrowska

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  1. Department Head Discovery Biology, Rhône-Poulenc Rorer Ltd, Dagenham Research Centre, RM10 7XS, Dagenham, Essex, England

    David Raeburn

  2. Department of Thoracic Medicine, Royal Brompton National Heart and Lung Institute, Dovehouse Street, SW3 6LY, London, England

    Mark A. Giembycz (Lecturer) (Lecturer)

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Dąbrowska, R. (1994). Actin and Thin-Filament-Associated Proteins in Smooth Muscle. In: Raeburn, D., Giembycz, M.A. (eds) Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation. Respiratory Pharmacology and Pharmacotherapy. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7681-0_2

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