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Enzymes and Proteins from Thermophilic Microorganisms Structure and Function pp 347–362Cite as

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Purification, Characterization and Mechanism of Action of Several Aminoacyl-tRNA Synthetases from Bacillus Stearothermophilus

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Part of the book series: Experientia Supplementum ((EXS,volume 26))

Abstract

The 20 aminoacyl-tRNAsynthetases, one specific for each amino acid, catalyse the following reaction:

$$a{{a}_{1}} + ATP + tRN{{A}_{1}}\overset{{aa - tRNAsynthetase, M{{g}^{{ + + }}}}}{\rightleftharpoons} a{{a}_{1}} - tRN{{A}_{1}} + AMP + P{{P}_{i}}$$

In vivo these reactions are extremely specific and constitute a key step in the overall protein biosynthesis process.

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Author information

Authors and Affiliations

  1. I.B.M.C., Strasbourg, France

    G. Dirheimer, R. Giege & G. Keith

  2. Laboratoire de Chimie Biologique, Université Libre de Bruxelles, 65 rue des Chevaux, B-1640, Rhode-St Genèse, Belgium

    H. Grosjean, J. Charlier, C. Darte, S. de Henau, R. Parfait & C. Takada

Authors
  1. H. Grosjean
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  2. J. Charlier
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  3. C. Darte
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  4. G. Dirheimer
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  5. R. Giege
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  6. S. de Henau
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  7. G. Keith
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  8. R. Parfait
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  9. C. Takada
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Editor information

Editors and Affiliations

  1. Eidgenössische Technische Hochschule, CH-8049, Zürich, Switzerland

    Herbert Zuber

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© 1976 Springer Basel AG

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Grosjean, H. et al. (1976). Purification, Characterization and Mechanism of Action of Several Aminoacyl-tRNA Synthetases from Bacillus Stearothermophilus. In: Zuber, H. (eds) Enzymes and Proteins from Thermophilic Microorganisms Structure and Function. Experientia Supplementum, vol 26. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7675-9_28

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  • DOI: https://doi.org/10.1007/978-3-0348-7675-9_28

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7677-3

  • Online ISBN: 978-3-0348-7675-9

  • eBook Packages: Springer Book Archive

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