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DNA Profiling in Veterinary Medicine

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Part of the book series: Methods and Tools in Biosciences and Medicine ((MTBM))

Abstract

The main applications for DNA profiling in domestic animals are identity and parentage control. Additional DNA-based tests are available for the diagnosis of genetic diseases and for the sexing of animals. The recent development of medium-density genetic linkage maps permits even initial mapping projects in domestic animal flocks (for a review see [1]). In horses, as well as other farm animals, selective breeding (e.g. for speed or jumping ability) requires exact lineage records. Therefore, spot-check parentage control is used extensively by most breed registries for a defined percentage (1–10%) of offspring from each year. Additional options used by some organizations are to test all offspring produced by artificial insemination and all males whose semen is collected for sale. The price of descendants is determined in part by the reputation of the lineage or the breeding value, thus assuring that the owner has a strong interest in establishing the correct breeding lines. In some special cases (e.g. questionable practices) the owner itself submits animals for testing. Parentage control in animals has relied on conventional testing methods [blood groups, serum proteins, red cell enzymes, major histocompatibility complex (MHC)] for several decades now. For obvious reasons (degree of polymorphism, standardization potential etc.) these methods are being replaced by more modern ones such as DNA fingerprinting or usage of microsatellites.

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© 1999 Birkhäuser Verlag

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Buitkamp, J., Antes, R., Wagner, V. (1999). DNA Profiling in Veterinary Medicine. In: Epplen, J.T., Lubjuhn, T. (eds) DNA Profiling and DNA Fingerprinting. Methods and Tools in Biosciences and Medicine. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7582-0_4

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  • DOI: https://doi.org/10.1007/978-3-0348-7582-0_4

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-7643-6018-4

  • Online ISBN: 978-3-0348-7582-0

  • eBook Packages: Springer Book Archive

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