Abstract
Since their introduction about 10 years ago, microsatellites have been demonstrated to be a powerful tool for genetic analysis of natural populations [1]. Microsatellites are easy to isolate, highly polymorphic and many individuals can be characterized for a number of loci.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Schlötterer C, Pemberton J (1998) The use of microsatellites for genetic analysis of natural populations — a critical review. In: R DeSalle, B Schierwater (eds): Molecular approaches to individuals, populations and species. Birkhäuser; Basel, 71–86
Schlötterer C, Tautz D (1992) Slippage synthesis of simple sequence DNA. Nucleic Acids Res 20: 211–215
Tautz D, Schlötterer C (1994) Simple Sequences. Curr Op Gen Dev 4: 832–837
Eisen JA (1999) Mechanistic explanations for variation in microsatellite stability within and between species. In: D Goldstein, C Schlötterer (eds): Microsatellites: evolution and applications, Oxford University Press; in press
Moran PAP (1975) Wandering distributions and electrophoretic profile. Theoretical Population Biology 8: 318–330
Goldstein DB, Ruiz Lineares A, Cavalli-Sforza LL, Feldman MW (1995) Genetic absolute dating based on microsatellites and the origin of modern humans. Proc Natl Acad Sci USA 92: 6723–6727
Di Rienzo A, Peterson AC, Garza JC, Valdes AM, Siatkin M, Freimer NB (1994) Mutational processes of simplesequence repeat loci in human populations. Proc Natl Acad Sci USA 91: 3166–3170
Garza JC, Siatkin M, Freimer NB (1995) Microsatellite allele frequencies in humans and chimpanzees with implications for constraints on allele size. Mol Biol Evol 12: 594–603
Goldstein DB, Pollock DD (1997) Launching microsatellites: a review of mutation processes and methods of phylogenetic inference. J Hered 88: 335–342
Chakraborty R, Kimmel M, Stivers DN, Davison LJ, Deka R (1997) Relative mutation rates at di-, tri- and tetranucleotide microsatellite loci. Proc Natl Acad Sci USA 94: 1041–1046
Harr B, Zangerl B, Brem G, Schlötterer C (1998) Conservation of locus specific microsatellite variability across species: a comparison of two Drosophila sibling species D. melanogaster and D. simulans. Mol Biol Evol 15: 176–184
Wierdl M, Dominska M, Petes TD (1997) Microsatellite instability in yeast: dependence on the length of the microsatellite. Genetics 146: 769–779
Jin L, Macaubas C, Hallmayer J, Kimura A, Mignot E (1996) Mutation rate varies among alleles at a microsatellite locus: phylogenetic evidence. Proc Natl Acad Sci USA 93: 15285–15288
Tautz D, Trick M, Dover GA (1986) Cryptic simplicity in DNA is a major source of genetic variation. Nature 322: 652–656
Hancock J (1996) Simple sequences in a “minimal” genome. Nature Genet 14: 14–15
Schlötterer C (1998) Are microsatellites really simple sequences? Curr Biol 8: R132-R134
Viard F, Franck P, Dubois MP (1998) Variation of microsatellite size homoplasy across electromorphs, loci and populations in three invertebrate species. J Mol Evol; 42–51
Jacobson DP, Schmeling P, Sommer SS (1993) Characterization of the patterns of polymorphism in a “cryptic repeat” reveals a novel type of hypervariable sequence. Am J Hum Genet 53: 443–450
Sommer SS, Tillotson VL, Vielhaber EL, Ketterling RP, Dutton CM (1994) “Cryptic” dinucleotide polymorphism in the 3′ region of the factor IX gene shows substantial variation among different populations. Hum Genet 93: 357–358
Bowcock AM, Ruiz-Lineares A, Tonfohrde J, Minch E, Kidd JR, Cavalli-Sforza LL (1994) High resolution of human evolutionary trees with polymorphic microsatellites. Nature 368: 455–457
Citri Y, Colot HV, Jacquier AC, Yu Q, Hall JC, Baltimore D, Rosbash M (1987) A family of unusual spliced biologically active transcripts encoded by a Drosophila melanogaster clock gene. Nature 326: 42–47
Rosato E, Peixoto AA, Barbujani G, Costa R, Kyriacou CP (1994) Molecular polymorphism in the period gene of Drosophila simulans. Genetics 138: 693–707
Schlötterer C (1995) Temperature-gradient gel electrophoresis as a screening tool for polymorphisms in multigene families. Electrophoresis 16: 722–728
Underhill PA, Jin L, Lin AA, Mehdi SQ, Jenkins T, Vollrath D, Davis RW, Cavalli-Sforza LL, Oefner PJ (1997) Detection of numerous Y chromosome biallelic polymorphism by denaturing high-performance liquid chromatography. Genome Res 7: 996–1005
Angers B, Bernatchez L (1997) Complex evolution of a salmonid microsatellite locus and its consequences in inferring allelic divergence from size information. Mol Biol Evol 14: 230–238
Estoup A, Tailliez C, Cornuet JM, Solignac M (1995) Size homoplasy and mutational processes of interrupted microsatellites in two bee species, Apis mellifera and Bombus terrestris (Apidae). Mol Biol Evol 12: 1074–1084
Schlötterer, C, Ritter, R, Harr, B and Brem, G (1998) High mutation rates of long microsatellite alleles in Drosophilia melangoaster provide evidence for allele specific mutation rates. Molecular Biology and Evolution 15, 1269–1274
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Birkhäuser Verlag
About this chapter
Cite this chapter
Schlötterer, C., Zangerl, B. (1999). The Use of Imperfect Microsatellites for DNA Fingerprinting and Population Genetics. In: Epplen, J.T., Lubjuhn, T. (eds) DNA Profiling and DNA Fingerprinting. Methods and Tools in Biosciences and Medicine. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7582-0_10
Download citation
DOI: https://doi.org/10.1007/978-3-0348-7582-0_10
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-7643-6018-4
Online ISBN: 978-3-0348-7582-0
eBook Packages: Springer Book Archive