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Angiotensin converting enzyme inhibition in the microcirculation

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ACE Inhibitors

Part of the book series: Milestones in Drug Therapy MDT ((MDT))

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Abstract

Microcirculation networks represent highly specialized segments of the general circulation in terms of structure and function. Definition of these segments is critical to establish the volume of blood contained, the endothelial surface exposed to the neighbouring fluid compartments, including the interstitial and cellular compartments, the lumen diameter and wall thickness of each segment. In fact, these structural characteristics determine a large part of the physiological functions of the vasculature, from hydrostatic pressure development to fluid and nutrient exchanges in peripheral organs.

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Authors and Affiliations

  1. Departments of Medicine (Nephrology), Physiology and Pharmacology, Institute of Pharmacology, University of Sherbrooke, Sherbrooke, Québec, Canada

    Gérard E. Plante & Tewfik Nawar

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  1. Gérard E. Plante
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  2. Tewfik Nawar
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Editors and Affiliations

  1. Department of Pharmacology, Institute of Pharmacology of Sherbrooke, Medical School, Sherbrooke University, J1H-5N4, Sherbrooke, PQ, Canada

    Pedro D’Orléans-Juste  & Gérard E. Plante  & 

  2. Departments of Medicine (Nephrology), Physiology and Pharmacology, Institute of Pharmacology, University of Sherbrooke, Sherbrooke, Québec, Canada

    Gérard E. Plante

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Plante, G.E., Nawar, T. (2001). Angiotensin converting enzyme inhibition in the microcirculation. In: D’Orléans-Juste, P., Plante, G.E. (eds) ACE Inhibitors. Milestones in Drug Therapy MDT. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7579-0_7

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  • DOI: https://doi.org/10.1007/978-3-0348-7579-0_7

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7581-3

  • Online ISBN: 978-3-0348-7579-0

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