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Advances in Aerobiology pp 243–248Cite as

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Lysosome Response and Cytoskeleton Alteration in Cell Cultures Exposed to Airborne Lead

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Part of the book series: Experientia Supplementum ((EXS,volume 51))

Abstract

We present here the delayed leakage of lysosome acridine orange in cell cultures exposed to lead acetate. Delayed leakage was accompanied by loss of actin. These responses were not elicited by sodium acetate but could be duplicated by extracts of air sample filters from a high air pollution area but not a cleaner air site.

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References

  1. Nakagawa, K., Asami, M. and Kuriyama, K.(1983) Some factors affecting enzyme release from cerebral lysosomes: inhibitory effects of lead. Japan J. Pharmacol. 33,9–15.

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  2. Orsi, E.V., Levins, P., Ames, G., Buonincontri, L., Holyk, N. and Balciunas, R. (1977) Human cell cultures as sentinal systems for monitoring air quality, pp. 637–650. in “Cell Culture and Its Applications”, R.T. Acton and J.D. Lynn (eds.) Academic Press, New York.

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  3. Orsi, E.V., Zois, W.J., and Baturay, O.F. (1983) Human cell cultures response to simulated and natural levels of air pollution. pp. 85–98. in “In Vitro Toxicity Testing of Environmental Agents, Part B”, A. Kolber, T.K. Wong, L.D. Grant, R.S. DeWoskin and T.J. Hughes (eds.) Plenum Pub. Co., New York and London.

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Author information

Authors and Affiliations

  1. Departments of Biology, Seton Hall University, 07079, So. Orange, N.J., USA

    Dr. Ernest V. Orsi, M. Bavlsik, R. Viera & M. Petersheim

  2. Departments Chemistry, Seton Hall University, South Orange, N.J., USA

    M. Petersheim & O. F. Baturay

  3. Technion Inc., Belleville, N.J., USA

    O. F. Baturay

Authors
  1. Dr. Ernest V. Orsi
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  2. M. Bavlsik
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  3. R. Viera
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  4. M. Petersheim
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  5. O. F. Baturay
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Editor information

Editors and Affiliations

  1. Herrengrabenweg 51, CH-4054, Basel, Switzerland

    G. Boehm

  2. Department of Research, Div. Dermatology/Allergology Kantonsspital, CH-4031, Basel, Switzerland

    Ruth M. Leuschner PhD

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© 1987 Birkhäuser Verlag Basel

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Orsi, E.V., Bavlsik, M., Viera, R., Petersheim, M., Baturay, O.F. (1987). Lysosome Response and Cytoskeleton Alteration in Cell Cultures Exposed to Airborne Lead. In: Boehm, G., Leuschner, R.M. (eds) Advances in Aerobiology. Experientia Supplementum, vol 51. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7491-5_41

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  • DOI: https://doi.org/10.1007/978-3-0348-7491-5_41

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7493-9

  • Online ISBN: 978-3-0348-7491-5

  • eBook Packages: Springer Book Archive

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