Skip to main content
SpringerLink
Log in

Glutamate 1-semialdehyde aminotransferase, a unique enzyme in chlorophyll biosynthesis

  • Conference paper
Book cover Biochemistry of Vitamin B6 and PQQ

Part of the book series: Advances in Life Sciences ((ALS))

  • 179 Accesses

Abstract

Glutamate 1-semialdehyde aminotransferase (GSA-AT) has been first described in barley. Gough and Kannangara [1] found an enzyme in the chloroplast stromal preparation of greening barley that catalyses the transamination of glutamate 1-semialdehyde (GSA) to δ-aminolevulinate (ALA). This is the final step of the C5 pathway which in three enzymatic reactions converts glutamate into ALA, the precursor for all tetrapyrroles [2, 3]. The primary structure of GSA-AT from barley has been obtained by partial amino acid sequence determination and nucleotide sequencing of a cDNA clone [4]. Subsequently, a number of bacterial and plant genes for GSA-AT have been sequenced [5–11].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kannangara, C.G. and Gough, S.P. (1978) Carlsberg Res. Commun. 43, 185–194

    CAS  Google Scholar 

  2. Beale, S.I. and Weinstein, J.D. (1990) in: Biosynthesis of Herne and Chlorophyll (Dailey, H.A., ed.) pp. 287–391, McGraw-Hill Publishing Co., New York

    Google Scholar 

  3. Smith, A. and Griffith, T.G. (1993) In Methods in Plant Biochemistry (Lea, P.J. ed.), Vol.9, pp. 299–343, Academic Press ltd., London

    Google Scholar 

  4. Grimm, B. (1990) Proc. Natl. Acad. Sci. USA 87, 4169–4173

    Article  PubMed  CAS  Google Scholar 

  5. Elliott, T., Avissar, Y.J., Rhie, G.E. and Beale, S.I. (1990) J. Bacteriol. 172, 7071–7084

    PubMed  CAS  Google Scholar 

  6. Grimm, B., Bull, A. and Breu, V. (1991) Mol. Gen. Genet. 225, 1–10

    Article  PubMed  CAS  Google Scholar 

  7. Hansson, M., Rutberg, L., Schröder, I. and Hederstedt, L. (1991) J. Bacteriol. 173, 2590–2599

    PubMed  CAS  Google Scholar 

  8. Sangwan, I. and O’Brian, M.R. (1993) Plant Physiol. 102, 829–836

    Article  PubMed  CAS  Google Scholar 

  9. Ilag, L.L., Kumar, A.M. and Söll, D. (1994) Plant Cell 6, 265–275

    Article  PubMed  CAS  Google Scholar 

  10. Matters G.L. and Beale, S.I. (1994) Plant Mol.Biol. 24, 617–629

    Article  PubMed  CAS  Google Scholar 

  11. Höfgen, R., Axelsen, K.B., Kannangara, C.G., SchüttkeI., Pohlenz, H.D., WillmitzerL., Grimm, B. and von Wettstein, D. (1994) Proc.Natl.Acad.Sci. 91, 1726–1730

    Article  PubMed  Google Scholar 

  12. Grimm, B., Smith, A.J., Kannangara, C.G. and Smith, M.A. (1991) J. Biol. Chem. 12495–12501

    Google Scholar 

  13. Smith, M.A., Kannangara, C.G., Grimm, B. and von Wettstein, D. (1991) Eur. J. Biochem. 202, 749–757

    Article  PubMed  CAS  Google Scholar 

  14. Smith, M.A., Grimm, B., Kannangara, C.G. and von Wettstein, D. (1991) Proc. Natl. Acad. Sci. USA 88, 9775–9779

    Article  PubMed  CAS  Google Scholar 

  15. Pugh, C.E., Harwood, J.L. and John, R.A. (1992) J. Biol. Chem. 267, 1584–1588

    PubMed  CAS  Google Scholar 

  16. Velick, S.F. and Vavra, J. (1962) J. Biol. Chem. 237, 2109–2122

    PubMed  CAS  Google Scholar 

  17. Smith, M.A., Kannangara, C.G. and Grimm, B. (1992) Biochemistry, 31 11249–11254

    Article  PubMed  CAS  Google Scholar 

  18. Grimm, B. Smith, M.A. and von Wettstein, D. (1992) Eur. J. Biochem. 206, 579–585 (1992)

    Article  PubMed  CAS  Google Scholar 

  19. Bull, A., Breu, V., Kannangara, C.G., Rogers, L.J. and Smith, A.J. (1990) Arch. Mircobiol. 154, 56–59

    CAS  Google Scholar 

  20. Horsch, R.B., Fry, J.E., Hoffmann, N.L., Eichholtz, D., Rogers S.G. and Fraley, R.T. (1985) Science 227, 1229–1231

    Article  CAS  Google Scholar 

  21. Murray, J.A.H. and Crockett, N. (1992) in Modern Cell Biology: Antisense RNA and DNA, ed. Murray, J.A.H. ( Wiley-Liss, New York ), Vol. 11, pp 1–49

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Pflanzengenetik und Kulturpflanzenforschung, Corrensstr.3, 06466, Gatersleben, Germany

    Bernhard Grimm

Authors
  1. Bernhard Grimm
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Dipartimento di Chimica Organica e Biologica, Università di Napoli “Federico II”, Via Mezzocannone 16, I-80134, Napoli, Italy

    G. Marino  & G. Sannia  & 

  2. Dipartimento di Scienze Biochimiche, Università di Roma “La Sapienza”, P.le Aldo Moro 5, I-00185, Roma, Italy

    F. Bossa

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Birkhäuser Verlag Basel/Switzerland

About this paper

Cite this paper

Grimm, B. (1994). Glutamate 1-semialdehyde aminotransferase, a unique enzyme in chlorophyll biosynthesis. In: Marino, G., Sannia, G., Bossa, F. (eds) Biochemistry of Vitamin B6 and PQQ. Advances in Life Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7393-2_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-7393-2_16

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7395-6

  • Online ISBN: 978-3-0348-7393-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation