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The General Approach to Cystic Fibrosis Pulmonary Infection in Mexico

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Cystic Fibrosis Pulmonary Infections: Lessons from Around the World

Part of the book series: Respiratory Pharmacology and Pharmacotherapy ((RPP))

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Summary

Serious research work on Cystic Fibrosis (CF) in Mexico started back in 1980. CF is still regarded as a rare disease, which accounts for its late diagnosis (4.4 years). CF patients have a life expectancy of only 9 years.

In this chapter we analyse what has been published in our literature on the basic respiratory aspects of the disease, as well as providing an epidemiologic and genetic overview of the situation in Mexico.

The actual incidence of CF is unknown. However. the genetic study of our patients in 4 CF centers showed that the main mutation (∆F508) appears with a frequency of 39 to 41%.

Pseudomonas aeruginosa prevails as the main pathogen (60 to 68%) with the isolation of some strains of Burkholderia pseudomallei and mallei (13%).

The annual mean number of out-patient visits to CF Care Centers is 3.1; 27% of patients are hospitalized for IV therapy for a mean of 18 days. Fifteen percent receive IV home therapy. with hypercapnia as the main pulmonary complication (20%).

Ethnic and economic factors hinder the development of more research programs and the establishment of additional Care Centers to provide better treatment to these patients.

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Authors and Affiliations

  1. Mexican Cystic Fibrosis Association, Altavista 21, CP 01000, Mexico D.F., Mexico

    Jose Luis Lezana-Fernandez & Douglas Maza-Gonzales

Authors
  1. Jose Luis Lezana-Fernandez
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  2. Douglas Maza-Gonzales
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Editor information

Editors and Affiliations

  1. Max von Pettenkofer-Institut, Ludwig-Maximilians-Universität, Pettenkoferstrasse 9a, D-80336, Munich, Germany

    Adolf Bauernfeind

  2. University of California at Irvine, 2801 Atlantic Avenue, 90801, Long Beach, California, USA

    Melvin I. Marks MD (Professor and Vice Chair of Pediatrics, Medical Director/Administrator) (Professor and Vice Chair of Pediatrics, Medical Director/Administrator)

  3. Long Beach Memorial Medical Center, Memorial Miller Children’s Hospital, 2801 Atlantic Avenue, 90801, Long Beach, California, USA

    Melvin I. Marks MD (Professor and Vice Chair of Pediatrics, Medical Director/Administrator) (Professor and Vice Chair of Pediatrics, Medical Director/Administrator)

  4. Department of Pediatrics, Faculty of Medicine, Göteborg University, S-416 85, Göteborg, Sweden

    Birgitta Strandvik MD, PhD (Professor of Pediatrics) (Professor of Pediatrics)

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© 1996 Birkhäuser Verlag Basel/Switzerland

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Lezana-Fernandez, J.L., Maza-Gonzales, D. (1996). The General Approach to Cystic Fibrosis Pulmonary Infection in Mexico. In: Bauernfeind, A., Marks, M.I., Strandvik, B. (eds) Cystic Fibrosis Pulmonary Infections: Lessons from Around the World. Respiratory Pharmacology and Pharmacotherapy. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7359-8_27

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  • DOI: https://doi.org/10.1007/978-3-0348-7359-8_27

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7361-1

  • Online ISBN: 978-3-0348-7359-8

  • eBook Packages: Springer Book Archive

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