Summary
Designed thiazine and thiazolidine derivatives as well as aspartic acid trimer have been synthetized and labelled with Tc-99m. Non-invasive animal experiments were carried out in New-Zealand type rabbits. In case of one thiazine-compound low but definite myocardial uptake was observed while three of the thiazolidine derivatives showed characteristic renal uptake. In case of aspartic acid trimer the myocardium was also visualized beside some hepatobiliary excretion.
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References
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© 1995 Birkhäuser Verlag Basel
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Környei, J., Szilvási, I., Nagy, Z., Földes, I. (1995). Tc-99m Labelling and Biodistribution of Designed Molecules. In: Bergmann, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7340-6_40
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DOI: https://doi.org/10.1007/978-3-0348-7340-6_40
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-0348-7342-0
Online ISBN: 978-3-0348-7340-6
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