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The Tissue Characterisation of Malignancy with Radionuclide Studies

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Radioactive Isotopes in Clinical Medicine and Research

Part of the book series: Advances in Pharmacological Sciences ((APS))

Summary

Radiolabelled agents are able to characterise tissue as malignant and this leads to new imaging approaches and therapies for the management of cancer patients.

Presentaion of the 21st International Symposium on Radioactive Isotopes in clinical medicine and research, Bad Gastein, Austria.

January 14th 1994.

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References

  1. Britton KE. Highlights of the Annual Meeting of the European Association of Nuclear Medicine, Lausanne 1993. Eur J Nucl Med 1994; 21: in press.

    Google Scholar 

  2. Chan S, Sikora K. The potential of oncogene products as tumour markers. Cancer Surveys 1987; 6: 185–207.

    PubMed  CAS  Google Scholar 

  3. Britton KE. The development of new radiopharmaceuticals. Eur J Nucl Med 1990; 10: 281–285.

    CAS  Google Scholar 

  4. Khalkhali L, Mena I, Jouanne E et al. Tc-99m-sesta MIBI prone breast imaging in patients with suspicion of breast cancer. J Nucl Med 1993; 34: 140 P.

    Google Scholar 

  5. Suga K, Nishigauchi K, Fujita T & Nakanishi T. Experimental evaluation of the usefulness of 201T1-chloride scintigraphy for monitoring radiotherapeutic effects. Nucl Med Commun 1994; 15:,128–139.

    Google Scholar 

  6. Flier JS, Mueckler MM, Usher P, Lodish HF. Elevated levels of glucose transport and transporter messenger RNA are induced by ras and sac oncogenes. Science 1982; 235: 1492 1495.

    Google Scholar 

  7. Lienhard GE, Shot JW, James DE, Mueckler RM. How cells absorb glucose. Sci Amer 1992: 226; 34–41.

    Google Scholar 

  8. Mertens J, Terriere D. The radiosynthesis of a new potential glucose transport protein tracer: 3-I-Phloretin. Eur J Nucl Med 1993; 20: 1000.

    Google Scholar 

  9. Weckesser M, Langen KJ, Hamacher B et al. Comparison of 123_I-“-methyl tyrosine SPECT and 11C-methionine PET in patients with brain tumours, initial results. Eur J Nucl Med 1994; 21: S6.

    Google Scholar 

  10. Ur E, Mather SJ, Bomanji J, Ellison D, Britton KE, Grossman AB. Pituitary imaging using a labelled somatostatin analogue in acromegaly. Clin Endocrinol 1993; 36: 147–150.

    Article  Google Scholar 

  11. Ur E, Bomanji J, Mather SJ, Britton KE, Wass JAH, Grossman AB, Besser GM. Localization of neuroendocrine tumours and insulinomas using radiolabelled somatostatin analogues, 123I-Tyr3-octreotide and 111In-pentetreotide. Clin Endocrinol 1993; 38: 501–506.

    Article  CAS  Google Scholar 

  12. Nocaudie-Calzeda M, Huglo D, Deveaux M et al. Iodine-123Tyr-3-Octreotide uptake in pancreatic endocrine tumours and in carcinoids in relation to hormonal inhibition by octreotide. J Nucl Med 1994; 35: 57–62.

    Google Scholar 

  13. Britton KE. The Bad Gastein Lecture. Nuclear Endocrinology, Radioactive isotopes in clinical medicine and research. Hofer R, Bergmann H, Sinzinger H. eds. Stuttgart 1992: 3–13.

    Google Scholar 

  14. Solanki KK, Bomanji J, Moyes J et al. A pharmacological guide to medicines which interfere with the biodistribution of radiolabelled meta-iodobenzyl guanidine (MIBG). Nucl Med Commun 1992; 13: 513–521.

    Article  PubMed  CAS  Google Scholar 

  15. Bomanji J, Levison DA, Flatman WD et al. Uptake of I-123 metaiodobenzylguanidine by phaeochromocytomas, other paragangliomas and neuroblastomas, a histopathological comparison. J Nucl Med 1987; 23: 973–978.

    Google Scholar 

  16. Virgolini I, Raderer M, Li SR et al. 123I-Vasoactive intestinal peptide scintigraphy VIP in colorectal cancer and endocrine tumours. Eur J Nucl Med 1993; 20: 847.

    Google Scholar 

  17. Michelot JM, Moreau MFC, Veyre AJ et al. Phase II scintigraphic clinical trial of malignant melanoma and metastases with Iodine-123-N-(2-Diethyl amino ethyl 4-Iodo benzamide). J Nucl Med 1993; 34: 1260–1266.

    PubMed  CAS  Google Scholar 

  18. Maffioli L, Mascheroni L, Castellani R et al. I-123-(s)IBZM: a potential tracer for melanoma metastases. Eur J Nucl Med 1993; 20: 974.

    Google Scholar 

  19. Britton KE, Granowska M. Radioimmunoscintigraphy in tumour identification. Cancer Surveys 1987; 6: 247–267.

    PubMed  CAS  Google Scholar 

  20. Britton KE, Granowska M, Mather SJ. Radiolabelled monoclonal antibodies in oncology 1: Technical aspects. Nucl Med Commun 1991; 12: 65–76.

    Article  PubMed  CAS  Google Scholar 

  21. Granowska M, Britton KE. Radiolabelled monoclonal antibodies in oncology 2: Clinical applications in diagnosis. Nucl Med Commun 1991; 12: 83–98.

    Article  PubMed  CAS  Google Scholar 

  22. Perkins AC, Pimm MV. Immunoscintigraphy: practical aspects and clinical applications. Chichester, Wiley-Liss 1991.

    Google Scholar 

  23. Burchell J, Gender S, Taylor Papadimitriou J et al. Development and characterisation of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res 1987; 47: 5476–5482.

    PubMed  CAS  Google Scholar 

  24. Granowska M, Britton KE, Mather SJ et al.

    Google Scholar 

  25. Radioimmunoscintigraphy with Technetium-99m-labelled monoclonal antibody, SM3, in gynaecological cancer. Eur J Nucl Med. 1993; 20: 483–489.

    Google Scholar 

  26. Granowska M, Britton KE, Mather SJ et al. Radioimmunoscintigraphy with Technetium-99m labelled monoclonal antibody, 1A3 in colorectal cancer. Eur J Nucl Med 1993; 20: 690–698.

    PubMed  CAS  Google Scholar 

  27. Siccardi AG, Buraggi GL, Callegaro L et al. Multicentre study of immunoscintigraphy with radiolabelled monoclonal antibodies in patients with melanoma. Cancer Research 1986; 46: 4817–4822.

    PubMed  CAS  Google Scholar 

  28. Bomanji J, Hungerford JL, Granowska M, Britton KE. Radioimmunoscintigraphy of ocular melanoma with 99mTc labelled cutaneous melanoma antibodies. Brit J Ophthalmol 1987; 71: 651–658.

    Article  CAS  Google Scholar 

  29. Baum RP, Niesen A, Goldberg L et al. A novel human chimeric antibody (Tc-99m C-174) for the staging of squamous head and neck cancer. Eur J Nucl Med 1993; 20: 856.

    Google Scholar 

  30. Goldenberg DM, Sharkey RM, Levine GL et al. Initial clinical imaging results with a new monoclonal antibody agent for B-cell lymphomas. Eur J Nucl Med 1993; 20: 875.

    Google Scholar 

  31. Chengazi VU, Feneley M, Granowska M et al. Prostatic radioimmunoscintigraphy - technique and pharmokinetics. Presentation to the British Association of Urological Surgeons. Br J Urol 1994 in press.

    Google Scholar 

  32. Stewart JSW, Hird V, Sullivan M, Snook D, Epenetos AA. Intraperitoneal radioimmunotherapy for ovarian cancer. Br J Obs Gyn 1989; 86: 529–536.

    Article  Google Scholar 

  33. Riva P, Tison V, Arista A et al. Radioimmunotherapy of gastrointestinal cancer and glioblastomas. Int J Biol Mark 1993; 8: 192–197.

    CAS  Google Scholar 

  34. Epenetos AA. Adjuvant therapy of ovarian cancer with radioactive monoclonal antibody. Nucl Med Commun 1992; 13: 218.

    Article  Google Scholar 

  35. Beierwaltes WH. The treatment of thyroid carcinoma with radioactive iodine. Semin Nucl Med 1976; 8: 79–94.

    Article  Google Scholar 

  36. Barrada M, Pateisky N, Schemper M et al. Survival of ovarian cancer patients after immunoscintigraphy using monoclonal antibodies. Poster Bad Gastein. 21st Symp. 1994.

    Google Scholar 

  37. Britton KE. Radioisotope therapy of cancer–past, present and future: an overview. Monoclonal Antibodies 2. Epenetos AA Ed, Chapman and Hall, London 1993; 429–439.

    Google Scholar 

  38. Britton KE, Mather SJ, Granowska M. Radiolabelled monoclonal antibodies in oncology III: Radioimmunotherapy. Nucl Med Commun 1991; 12: 333–347.

    CAS  Google Scholar 

  39. Paganelli G, Magnani P, Zito F et al. Three step monoclonal antibody tumour targetting in carcinoembryonic antigen-positive patients. Cancer Res 1991; 51: 5960–5966.

    PubMed  CAS  Google Scholar 

  40. Paganelli G, Malcovati M, Fazio F. Monoclonal antibody pretargetting techniques for tumour localisation: the avidin-biotin system. Nucl Med Commun. 1991; 12: 211–234.

    Article  PubMed  CAS  Google Scholar 

  41. Britton KE. Radiobiology workshop: An elemental dose approach to radioimmunotherapy. Monoclonal Antibodies 2. Epenetos AA Ed. Chapman and Hall, London 1993; 383–390.

    Google Scholar 

  42. Bos ES, Kuipjers WHA, Kaspersen FM. DNA-DNA hybridisation, a novel two step approach in radioimmunotherapy. Proc 10th Int Hammersmith Conf. Advances in the applications of monoclonal antibodies in clinical oncology, Paphos. 1993; 23–24.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, St Bartholomew’s Hospital, London, EC1A 7BE, UK

    Professor Keith Britton

Authors
  1. Professor Keith Britton
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Editor information

Editors and Affiliations

  1. Department of Biomedical Engineering and Physics, University of Vienna, Dr. Heckmannstr. 4, A-1140, Vienna, Austria

    Helmar Bergmann

  2. Department of Nuclear Medicine, University of Vienna, Nadlergasse 1, A-1090, Vienna, Austria

    Helmut Sinzinger

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© 1995 Birkhäuser Verlag Basel

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Britton, K. (1995). The Tissue Characterisation of Malignancy with Radionuclide Studies. In: Bergmann, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7340-6_38

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  • DOI: https://doi.org/10.1007/978-3-0348-7340-6_38

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7342-0

  • Online ISBN: 978-3-0348-7340-6

  • eBook Packages: Springer Book Archive

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