Summary
The new Tc-99m-labeled F(ab′)2 fragments of the monoclonal anti-CEA antibody F023C5 were investigated in 17 patients suffering from recurrent colorectal cancer. In 29% of patients, previously unexpected lesions could be identified. Four patients were also investigated with whole IgGI anti-CEA BW 431/26, where sensitivity was found to be lower, tumor/background ratio of positive lesions (esp. liver metastases) higher.
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© 1995 Birkhäuser Verlag Basel
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Behr, T., Becker, W., Klein, M., Stühler, C., Scheele, J., Wolf, F. (1995). Immunoscintigraphy of Colorectal Cancer with Tc-99m-Labeled F(ab′)2 Fragments of the Anti-CEA MoAb F023C5 First Clinical Results. In: Bergmann, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7340-6_27
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DOI: https://doi.org/10.1007/978-3-0348-7340-6_27
Publisher Name: Birkhäuser Basel
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