Summary
Treating alcoholism reduces many alcohol-related social, economic, and medical problems. A historical lack of support for alcoholism treatment and for alcoholism treatment research is disappearing, and significant progress is being made toward developing new and improved treatments. Current research findings are the basis of this “Outlook” which is divided into three levels of confidence: clear extrapolations from present research, extrapolations that are reasonable but uncertain, and predictions that attempt to guess the unguessable. It concludes that the future looks promising for new and improved alcoholism treatments.
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References
Alcoholics Anonymous (1990) 1989 Membership Survey, A.A. World Services, New York, New York, Appendix C, p. 12.
Ballenger, J.C. and Post, R.M. (1978) Kindling as a model for alcohol withdrawal syndromes. Br. J. Addict.133: 1–14.
Baxter, L.R., Schwartz, J.M., Bergman, K.S., Szuba, M.P., Guze, B.H., Mazziotta, J.C., Alazarki, A. Selin, C.E., Ferng, H.-K., Munford, P. and Phelps, M.E. (1992) Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Arch. Gen. Psychiatry49: 681–689.
Bruno, F. (1989) Buspirone in the treatment of alcoholic patients. Psychopathology22: 49–59.
Carlsson, A.V., Hiltunen, A.J., Beck, O., Stibler, H. and Borg, S. (1993) Detection of relapses in alcohol-dependent patients: Comparison of carbohydrate-deficient transferrin in serum, 5hydroxytryptophon in urine, and self-reports. Alcoholism: Clin. Exp. Res.17: 703–708.
Doms, W., Ostrow, D.G., Anton, R., Cushman, P., Collins, J.F., Schaefer, M., Charles, H.L., Desai, P., Hayashidam, M., Malkerneker, U., Willenbring, M., Fiscella, R. and Sather, M.R. (1989) Lithium treatment of depressed and nondepressed alcoholics. J. Am. Med. Assoc.262: 1646–1652.
Fuller, R.K., Branchey, L, Brightwell, D.R., Derman, R.M., Emrick, D.D., Iber, F.L., James, K.E., Lacoursiere, R.B., Lee, K.K., Lowenstam, I., Maany, I., Neiderhiser, D., Nocks, J.J. and Shaw, S. (1986) Disulfiram treatment of alcoholism: A Veterans Administration Cooperative Study. J. Am. Med. Assoc.256: 1449–1455.
Kranzler, H.R. and Meyer, R.E. (1989) An open trial of buspirone in alcoholics. J. Clin. Psychopharmacol.9: 379–380.
Malcolm, R. Anton, F.R., Randall, C.L., Johnston, A. Brady, K. and Thevos, A. (1992) A placebo-controlled trial of buspirone in anxious inpatient alcoholics. Alcoholism: Clin. Exp. Res.16: 1007–1013.
Marlatt, G.A. and Gordon, J.R. (1980) Determinants of relapse: Implications of the maintenance of behavior change. In: Davidson, P. and Davidson, S.M. (eds.): Behavioral Medicine: Changing Health Lifestyles. New York, Brunner/Mazel, pp. 410–452.
Moore, R.D., Bone, L.R., Geller, G., Mamon, J.A., Stokes, E.J. and Levine, D.M. (1989) Prevalence, detection, and treatment of alcoholism in hospitalized patients. J. Am. Med. Assoc.261: 403–407.
O’Malley, S.S., Jaffe, A.J., Chang, G., Schottenfeld, R.S., Meyer, R.E. and Rounsaville, B. (1992) Naltrexone and coping skills therapy for alcohol dependence: A controlled study. Arch. Gen. Psychiatry49: 881–887.
Sapolsky, R.M, Krey, L.C. and McEwen, B.S. (1986) The neuroendocrinology of stress and aging: The glucocorticoid cascade hypothesis. Endocrine Rev. 7: 284–301.
Sullivan, J.T., Sykora, K., Schneiderman, J., Naranjo, C.A. and Sellers, E.M. (1989) Assessment of alcohol withdrawal: The revised clinical institute withdrawal assessment for alcohol scale (CIWA-AR). Br. J. Addic.84: 1353–1357.
Tiffany, S.T. (1990) A cognitive model of drug urges and drug-use behavior: Role of automatic and nonautomatic processes. Psychol. Rev.97: 147–168.
Tollefson, G.D., Montague-Clouse, J. and Tollefson, S.L. (1992) Treatment of comorbid generalized anxiety in a recently detoxified alcoholic population with a selective serotonergic drug (buspirone). J. Clin. Psychopharm.12: 19–26.
Volpicelli, J.R., Alterman, A.I., Hayashida, M. and O’Brien, C.P. (1992) Naltrexone in the treatment of alcoholdependence. Arch. Gen. Psychiatry 49: 876–880.
Wahlestedt, C., Golanov, E., Yamamoto, S., Yee, F., Ericson, H., Yoo, H., Inturrisi, C.E. and Reis, D.J. (1993) Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature363: 260–263.
Walsh, D.C., Hingson, R.W., Merrigan, D.M., Levenson, S.M., Cupples, L.A., Heeren, T., Coffman, G.A., Becker, C.A., Barker, T.A., Hamilton, S.K., McGuire, T.G. and Kelly, C.A. (1991) A randomized trail of treatment options for alcohol-abusing workers. N. Engl. J. Med.325: 775–782.
Yeomans, M.R., Wrigth, P., Macleod, H.A. and Critchley, J.H. (1990) Effects of nalmefene on feeding in humans. Psychopharmacology100: 426–432.
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© 1994 Birkhäuser Verlag Basel/Switzerland
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Gordis, E. (1994). Outlook: Prospects for alcoholism treatment. In: Jansson, B., Jörnvall, H., Rydberg, U., Terenius, L., Vallee, B.L. (eds) Toward a Molecular Basis of Alcohol Use and Abuse. Experientia, vol 71. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7330-7_39
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DOI: https://doi.org/10.1007/978-3-0348-7330-7_39
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