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Comparative Molecular Neurobiology pp 390–413Cite as

The electrophysiological pharmacology of neurotransmitter receptors on locust neuronal somata

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Part of the book series: EXS ((EXS,volume 63))

Summary

The mechanically-dissociated neuronal somata from the thoracic ganglia of locusts (Schistocerca gregaria and Locusta migratoria) respond in a characteristic manner to virtually all putative insect neurotransmitters, as well as to some of the few neuropeptides tested so far. The isolated somata remain eleetrophysiologically viable in vitro for many hours so that it has been possible to characterize in detail the pharmacology and ionic- and voltage-dependences of many of these responses under voltage-clamp conditions. Our current knowledge of these properties is reviewed and compared with the corresponding data available from insect synaptic responses.

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References

  • Abalis, I. M., Eldefrawi, M. E. and Eldefrawi, A. T. (1983) Biochemical identification of putative GABA/benzodiazepine receptors in house fly thorax muscles. Pestic. Biochem. Physiol 20, 39–48.

    Article  Google Scholar 

  • Augustine, G. J., Fetterer, R. and Watson, W. H. (1982) Amine modulation of the neurogenic Limulus heart. J. Neurobiol. 13, 61–74.

    Article  Google Scholar 

  • Baines, R. A. and Downer, R. G. H. (1991) Pharmacological characterization of a 5-hydroxy- tryptamine-sensitive receptor/adenylate cyclase complex in the mandibular closer muscles of the cricket, Gryllus domestica. Archs Insect Biochem. Physiol. 16, 153–163.

    Article  Google Scholar 

  • Barker, J. L. and Mathers, D. A. (1981) GABA analogues activate channels of different duration on cultured mouse spinal neurons. Science 212, 258–361.

    Article  Google Scholar 

  • Benson, J. A. (1984) Octopamine alters rhythmic activity in the isolated cardiac ganglion of the crab, Portunus sanguinolentus. Neurosci. Lett. 44, 59–64.

    Article  Google Scholar 

  • Benson, J. A. (1988a) Pharmacology of a locust thoracic ganglion somal nicotinic acetylcholine receptor, in: Nicotinic Acetylcholine Receptors in the Nervous System. NATO ASI Series H, vol. 25, pp. 227–240. Eds F. Clementi, C. Gotti and E. Sher. Springer-Verlag, Berlin.

    Chapter  Google Scholar 

  • Benson, J. A. (1988b) Transmitter receptors on insect neuronal somata: GABAergic and cholinergic pharmacology, in: The Molecular Basis of Drug and Pesticide Action - Neurotox’88, pp. 193–206. Ed. G. G. Lunt. Elsevier Biomedical, Amsterdam.

    Google Scholar 

  • Benson, J. A. (1988c) Bicuculline blocks the response to acetylcholine and nicotine but not to muscarine or GABA in isolated insect neuronal somata. Brain Res. 458, 65–71.

    Article  Google Scholar 

  • Benson, J. A. (1989a) M j-like muscarinic receptors mediate cholinergic activation of an inward current in isolated neuronal somata from locust thoracic ganglia. Soc. Neurosci., Abstr. 15, 365.

    Google Scholar 

  • Benson, J. A. (1989b) Insect nicotinic acetylcholine receptors as targets for insecticides, in: Progress and Prospects in Insect Control. BCPC Monograph No. 43, pp. 59–70. Ed. N. R. McFarlane. British Crop Protection Council, Farnjiam, England.

    Google Scholar 

  • Benson, J. A. (1989c) A novel GABA receptor in.Jhe heart of a primitive arthropod, Limulus polyphemus. J. exp. Biol. 147, 421–438.

    Google Scholar 

  • Benson, J. A. (1990) Nitromethylene heterocycle insecticides are antagonists at insect neuronal nicotinic receptors, in: Seventh International Congress of Pesticide Chemistry, vol. 1, p. 348. Eds H. Frehse, E. Kesseler-Schmitz and S. Conway. International Union of Pure and Applied Chemistry, Hamburg.

    Google Scholar 

  • Benson, J. A. (1992a) Natural and synthetic toxins at insect receptors and ion channels: the search for insecticide leads and target sites, in: The Molecular Basis of Drug and Pesticide Action - Neurotox’91, pp. 57–70. Ed. I. R. Duce. Elsevier Applied Science, London and New York.

    Google Scholar 

  • Benson, J. A. (1992b) Electrophysiological pharmacology of the nicotinic and muscarinic acetylcholine responses of isolated neuronal somata from locust thoracic ganglia. J. exp. Biol. (in press).

    Google Scholar 

  • Benson, J. A. and Cooke, I. M. (1984) Driver potentials and the organization of rhythmic bursting in crustacean ganglia. Trends NeuroSci. 7, 85–91.

    Article  Google Scholar 

  • Benson, J. A., Kaufmann, L., Hue, B., Schurmann, F., Gsell, L. and Piek, T. (1992a) The physiological action of analogues of philanthotoxin-433 at insect nicotinic receptors. Comp. Biochem. Physiol, (in press)

    Google Scholar 

  • Benson, J. A. and Levitan, I. B. (1983) Serotonin increases an anomalously rectifying K + current in the Aplysia neuron R15. Proc. Natl Acad. Sci. USA 80, 3522–3525.

    Article  Google Scholar 

  • Benson, J. A. and Neumann, R. (1987) Nicotine and muscarine evoke different responses in isolated, neuronal somata from locust thoracic ganglia. Soc. Neurosci., Abstr. 13, 938.

    Google Scholar 

  • Benson, J. A., Schurmann, F., Kaufmann, L., B., Gsell, L. and Piek, T. (1992b) Inhibition of dipteran larval neuromuscular synaptic transmission by analogues of philanthotoxin-433: a structure-activity study. Comp. Biochem. Physiol. 102C, 267–272.

    Google Scholar 

  • Bermudez, I. and Beadle, D. J. (1989) High-affinity uptake of [3H]serotonin in cultured neurones of the cockroach Periplaneta americana. Archs Insect Biochem. Physiol. 12, 253–266.

    Article  Google Scholar 

  • Bermudez, I., Beadle, D. J. and Benson, J. A. (1990) Multiple serotonin-activated currents in isolated, neuronal somata from locust thoracic ganglia. Soc. Neurosci., Abstr. 16, 857.

    Google Scholar 

  • Bermudez, I., Beadle, D. J. and Benson, J. A. (1992) Multiple serotonin-activated currents in isolated, neuronal somata from locust thoracic ganglia. J. exp. Biol. 165, 43–60.

    Google Scholar 

  • Bermudez, I., Hietter, H., Trifilieff, E., Beadle, D. J. and Luu, B. (1991) Effects of novel peptides from the Corpora Cardiaca of Locusta on insect central neurones. Pestic. Sci. 32, 523–524.

    Google Scholar 

  • Blackman, J. G., Ginsborg, B. L. and House, C. R. (1979) On the effect of iontophoretically applied dopamine on salivary gland cells of Nauphoeta cinerea. J. Physiol. 287, 67–80.

    Google Scholar 

  • Callec, J.-J. (1974) Synaptic transmission in the central nervous system of insects, in: Insect Neurobiology, pp. 119–185. Ed. J. E. Treherne. Elsevier/North-Holland, Amsterdam.

    Google Scholar 

  • Callec, J.-J. and Boistel, J. (1967) Les effets de l’acétylcholine aux niveaux synaptiques et somatiques dans le cas du dernier ganglion abdominal de la Blatte Periplaneta americana. C. R. Séances Soc. Biol. Paris 161, 442–446.

    Google Scholar 

  • Callec, J.-J. and Boistel, J. (1971) Rôle possible du GABA comme médiateur inhibiteur du système de fibres géantes chez la blatte (Periplaneta americana). J. Physiol. (Paris) 63, 119A.

    Google Scholar 

  • Carr, C. E. and Fourtner, C. R. (1980) Pharmacological analysis of a monosynaptic reflex in the cockroach, Periplaneta americana. J. exp. Biol. 86, 259–273.

    Google Scholar 

  • Cooke, I. M. and Sullivan, R. E. (1982) Hormones and neurosecretion, in: The Biology of Crustacea, vol. 3, pp. 205–290. Eds H. Atwood and D. Sandeman. Academic Press, New York.

    Google Scholar 

  • David, J. A. and Sattelle, D. B. (1984) Actions of cholinergic pharmacological agents on the cell body membrane of the fast coxal depressor motoneurone of the cockroach (Periplaneta americana). J. exp. Biol. 108, 119–136.

    Google Scholar 

  • Davis, J. L. P. and Pitman, R. M. (1991) Characterization of receptors mediating the actions of dopamine on an identified inhibitory motoneurone of the cockroach. J. exp. Biol. 155, 203–217.

    Google Scholar 

  • Davis, N. T. (1987) Neurosecretory neurons and their projections to the serotonin neurohemal system of the cockroach Periplaneta americana (L.), and identification of mandibular and maxillary neurons associated with this system. J. comp. Neurol. 259, 604–621.

    Article  Google Scholar 

  • Drummond, A. H., Benson, J. A. and Levitan, I. B. (1980) Serotonin-induced hyperpolarization of an identified Aplysia neuron is mediated by cyclic AMP. Proc. Natl Acad. Sci. USA 77, 5013–5017.

    Article  Google Scholar 

  • Dubas, F. (1990) Inhibitory effect of L-glutamate on the neuropile arborizations of flight motoneurones in locusts. J. exp. Biol. 148, 501–508.

    Google Scholar 

  • Dubas, F. (1991) Actions of putative amino acid neurotransmitters on the neuropile arborizations of locust flight motoneurones. J. exp. Biol. 155, 337–356.

    Google Scholar 

  • Duce, I. R. (1988) Glutamate, in: Comparative Invertebrate Neurochemistry, pp. 42–89. Eds G. G. Lunt and R. W. Olsen. Croom Helm, London and Sydney.

    Chapter  Google Scholar 

  • Dudai, Y. and Zvi, S. (1984) [3H]Serotonin binds to two classes of sites in Drosophila head homogenate. Comp. Biochem. Physiol. 77C, 305–309.

    Google Scholar 

  • Eldefrawi, A. T. and Eldefrawi, M. E. (1988) Acetylcholine, in: Comparative Invertebrate Neurochemistry, pp. 1–41. Eds G. G. Lunt and R. W. Olsen. Croom Helm, London and Sydney.

    Chapter  Google Scholar 

  • Elekes, K. and Hustert, R. (1988) The efferent innervation of the genital chamber by an identified serotonergic neuron in the female cricket Acheta domestica. Cell Tiss. Res. 252, 449–457.

    Article  Google Scholar 

  • Evans, P. D. (1980) Biogenic amines in the insect nervous system. Adv. Insect Physiol. 15, 317–473.

    Article  Google Scholar 

  • Evans, P. D. (1981) Multiple receptor types for octopamine in the locust. J. Physiol. 318, 99–122.

    Google Scholar 

  • Evans, P. D. (1985) Octopamine, in: Comprehensive Insect Biochemistry, Physiology and Pharmacology, pp. 499–530. Eds G. A. Kerkut and L. Gilbert. Pergamon Press, Oxford.

    Google Scholar 

  • Flanagan, T. R. J. and Berlind, A. (1984) Serotonin modulation of the release of sequestered [3H]serotonin from nerve terminals in an insect neurohaemal organ in vitro. Brain Res. 306, 243–250.

    Article  Google Scholar 

  • Florey, E. and Rathmayer, M. (1978) The effects of octopamine and other amines on the heart and on neuromuscular transmission in decapod crustaceans: further evidence for a role as neurohormone. Comp. Physiol. Biochem. 61C, 229–237.

    Article  Google Scholar 

  • Freschi, J. E. and Livengood, D. R. (1989) Membrane currents underlying muscarinic cholinergic excitation of motoneurons in lobster cardiac ganglion. J. Neurophysiol. 62, 984–995.

    Google Scholar 

  • Gahwiler, B. H., Maurer, R. and Wuthrich, H. J. (1984) Pitrazepin, a novel GABAa antagonist. Neurosci. Lett. 45, 311–316.

    Article  Google Scholar 

  • Goldstein, R. S. and Camhi, J. M. (1991) Different effects of the biogenic amines dopamine, serotonin and octopamine on the thoracic and abdominal portions of the escape circuit in the cockroach. J. comp. Physiol. 168, 103–112.

    Article  Google Scholar 

  • Goodman, C. S. and Spitzer, N. C. (1980) Embryonic development of neurotransmitter receptors in grasshoppers, in: Receptors for Neurotransmitters, Hormones and Pheromones in Insects, pp. 195–207. Eds. D. B. Sattelle, L. M. Hall and J. G. Hildebrand. Elsevier/North- Holland, Amsterdam.

    Google Scholar 

  • Grega, D. S. and Sherman, R. G. (1975) Responsiveness of neurogenic hearts to octopamine. Comp. Physiol. Biochem. 52C, 2–8.

    Google Scholar 

  • Guillen, A., Haro, A. and Municio, A. M. (1989) A possible new class of octopamine receptors coupled to adenylate cyclase in the brain of the dipterous Ceratitis capitata. Pharmacological characterization and regulation of 3H-octopamine binding. Life Sci. 45, 655–662.

    Article  Google Scholar 

  • Hancox, J. C. and Pitman, R. M. (1991) Plateau potentials drive axonal impulse bursts in insect motoneurons. Proc. Roy. Soc. London B 244, 33–38.

    Article  Google Scholar 

  • Hardie, R. C. (1987) Is histamine a neurotransmitter in insect photoreceptors? J. comp. Physiol. 161, 201–213.

    Article  Google Scholar 

  • Hardie, R. C. (1989) A histamine-activated chloride channel involved in neurotransmission at a photoreceptor synapse. Nature (London) 339, 704–706.

    Article  Google Scholar 

  • Homberg, U. and Hildebrand, J. G. (1989) Serotonin immunoreactivity in the optic lobes of the sphinx moth Manduca sexta and colocalization with FMRFamide and SCPB immuno-reactivity. J. comp. Neurol. 288, 243–253.

    Article  Google Scholar 

  • Horseman, B. G., Seymour, C., Bermudez, I. and Beadle, D. J. (1988) The effects of L-glutamate on cultured insect neurones. Neurosci. Lett. 85, 65–70.

    Article  Google Scholar 

  • Hue, B. (1991) Functional assay for GABA receptor subtypes of a cockroach giant interneuron. Archs of Insect Biochemistry and Physiology 18, 147–157.

    Article  Google Scholar 

  • Kaufmann, L. and Benson, J. A. (1991) Characterisation of a locust neuronal octopamine response. Soc. Neurosci., Abstr. 17, 277.

    Google Scholar 

  • Kerkut, G. A., Pitman, R. M. and Walker, R. J. (1969a) Sensitivity of neurones of the insect central nervous system to iontophoretically applied acetylcholine or GABA. Nature (London) 222, 1075–1076.

    Article  Google Scholar 

  • Kerkut, G. A., Pitman, R. M. and Walker, R. J. (1969b) Iontophoretic application of acetylcholine and GABA onto insect central neurones. Comp. Biochem. Physiol. 31, 611–633.

    Article  Google Scholar 

  • Knipper, M. and Breer, H. (1988) Subtypes of muscarinic receptors in insect nervous system. Comp. Biochem. Physiol. 90C, 275–280.

    Google Scholar 

  • Knipper, M. and Breer, H. (1989) Muscarinic receptors modulating acetylcholine release from insect synaptosomes. Comp. Biochem. Physiol. 93C, 287–292.

    Article  Google Scholar 

  • Kuffler, S. W. and Edwards, C. (1958) Mechanism of gamma aminobutyric acid (GABA) action and its relation to synaptic inhibition. J. Neurophysiol. 21, 589–610.

    Google Scholar 

  • Le Corronc., H., Lapied, B. and Hue, B. (1991) M2-like presynaptic receptors modulate acetylcholine release in the cockroach (Periplaneta americana) central nervous system. J. Insect Physiol. 37, 647–652.

    Article  Google Scholar 

  • Lees, G., Beadle, D. J., Neumann, R. and Benson, J. A. (1987) Responses to GABA by isolated insect neuronal somata: pharmacology and modulation by a benzodiazepine and a barbiturate. Brain Res. 401, 267–278.

    Article  Google Scholar 

  • Lees, G., Neumann, R., Beadle, D. J. and Benson, J. A. (1985) Flunitrazepam enhances responses induced by 4-aminobutyric acid and muscimol in freshly dissociated locust central neuronal somata. Pestic. Sci. 16, 534.

    Google Scholar 

  • Lummis, S. C. R. and Sattelle, D. B. (1985) Binding sites for 4-aminobutyric acid and benzodiazepines in the central nervous system of insects. Pestic. Sci. 16, 695–697.

    Article  Google Scholar 

  • Marder, E. and Paupardin-Tritsch, D. (1978) The pharmacological properties of some crustacean neuronal acetylcholine, y -aminobutyric acid, and L-glutamate responses. Physiol. 280, 213–236.

    Google Scholar 

  • Miller, M. W., Benson, J. A. and Berlind, A. (1984) Excitatory effects of dopamine on the cardiac ganglion of the crabs Portunus sanguinolentus and Podophthalmus vigil. J. exp. Biol. 108, 97–118.

    Google Scholar 

  • Nassel, D. (1987) Serotonin and serotonin-immunoreactive neurons in the nervous system of insects. Progr. Neurobiol. 30, 1–85.

    Article  Google Scholar 

  • Neumann, R., Lees, G., Beadle, D. J. and Benson, J. A. (1987) Responses to GABA and other neurotransmitters in insect central neuronal somata in vitro, in: Sites of Action for Neurotoxic Pesticides, pp. 25–43. Eds R. M. Hollingworth and M. B. Green. American Chemical Society, Washington, DC.

    Chapter  Google Scholar 

  • Orchard, I. (1982) Octopamine in insects: neurotransmitter, neurohormone, and neuromodulator. Canad. J. Zool. 60, 659–669.

    Article  Google Scholar 

  • Orr, G. L., Gole, J. W. D., Notman, H. J. and Downer, R. G. H. (1987) Pharmacological characterisation of the dopamine-sensitive adenylate cyclase in the cockroach brain: evidence for a distinct dopamine receptor. Life Sci. 41, 2705–2715.

    Article  Google Scholar 

  • Ozoe, Y., Fukuda, K., Mochida, K. and Nakamura, T. (1989) Actions of benzodiazepines on the housefly. 3. In vitro binding of [3H]Ro 5-4864 responding to GABA receptor ligands. Comp. Biochem. Physiol. 93C, 193–199.

    Google Scholar 

  • Piek, T. (1985) Neurotransmission and neuromodulation of skeletal muscles, in: Comprehensive Insect Biochemistry, Physiology and Pharmacology, pp. 55–118. Eds G. A. Kerkut and L. Gilbert. Pergamon Press, Oxford.

    Google Scholar 

  • Pitman, R. (1985) Nervous system, in: Comprehensive Insect Biochemistry, Physiology and Pharmacology, pp. 5–54. Eds G. A. Kerkut and L. Gilbert. Pergamon Press, Oxford.

    Google Scholar 

  • Pitman, R. M. and Baker, J. R. (1989) Dopamine responses recorded from a common inhibitory motoneurone of the cockroach (Periplaneta americana). Comp. Biochem. Physiol. 92C, 245–251.

    Article  Google Scholar 

  • Pitman, R. M. and Davis, J. P. L. (1988) Pharmacological differentiation of responses to dopamine, octopamine and noradrenaline recorded from a cockroach motoneurone. Pestic. Sci. 24, 311–323.

    Article  Google Scholar 

  • Pitman, R. M. and Kerkut, G. A. (1970) Comparison of the actions of iontophoretically applied acetylcholine and gamma aminobutyric acid with the EPSP and IPSP in cockroach central neurons. Comp. gen. Pharmacol. 1, 221–230.

    Article  Google Scholar 

  • Ramirez, J.-M. and Pearson, K. G. (1991) Octopamine induces bursting and plateau potentials in insect neurones. Brain Res. 549, 332–337.

    Article  Google Scholar 

  • Rehder, V., Bicker, G. and Hammer, M. (1987) Serotonin-immunoreactive neurons in the antennal lobes and suboesophageal ganglion of the honeybee. Cell Tiss. Res. 247, 59–66.

    Article  Google Scholar 

  • Robinson, T. N., Lunt, G. G., Battenby, M. K., Irving, S. N. and Olsen, R. W. (1985) Insect ganglia contain [3H]flunitrazepam-binding sites. Biochem. Soc. Trans. 13, 716–717.

    Google Scholar 

  • Robinson, T. N. and Olsen, R. W. (1988) GABA, in: Comparative Invertebrate Neurochemistry, pp. 90–123. Eds G. G. Lunt and R. W. Olsen. Croom Helm, London and Sydney.

    Chapter  Google Scholar 

  • Roeder, K. D. and Roeder, S. (1939) Electrical activity in the isolated ventral nerve cord of the cockroach. I. The action of pilocarpine, nicotine, eserine and acetylcholine. J. cell. comp. Physiol. 14, 1–9.

    Article  Google Scholar 

  • Roeder, T. (1990a) High-affinity antagonists of the locust neuronal octopamine receptor. Eur. J. Pharmacol. 191, 221–224.

    Article  Google Scholar 

  • Roeder, T. (1990b) Histamine Hj-receptor-like binding sites in the locust nervous tissue. Neurosci. Lett. 116, 331–335.

    Article  Google Scholar 

  • Roeder, T. and Gewecke, M. (1990) Octopamine receptors in locust nervous tissue. Biochem. Pharmacol. 39, 1793–1797.

    Article  Google Scholar 

  • Sattelle, D. B., David, J. A., Harrow, I. D. and Hue, B. (1980) Actions of a-bungarotoxin on identified insect central neurones, in: Receptors for Neurotransmitters, Hormones and Pheromones in Insects, pp. 125–139. Eds D. B. Sattelle, L. M. Hall and J. G. Hildebrand. Elsevier/North-Holland, Amsterdam.

    Google Scholar 

  • Sattelle, D. B., Lummis, S. C. R., Wong, J. F. H. and Rauh, J. J. (1991) Pharmacology of insect GABA receptors. Neurochem. Res. 16, 363–374.

    Article  Google Scholar 

  • Scott, R. H. and Duce, I. R. (1987) Pharmacology of the GABA receptors on skeletal muscle fibres of the locust (Schistocerca gregaria). Comp. Biochem. Physiol. 86C, 305–311.

    Article  Google Scholar 

  • Shankland, D. L., Rose, J. A. and Donniger, C. (1971) The cholinergic nature of the cercal nerve-giant fibre synapse in the sixth abdominal ganglion of the cockroach, Periplaneta americana (L.). J. Neurobiol. 2, 247–262.

    Article  Google Scholar 

  • Shimahara, T., Pichón, Y., Lees, G., Beadle, C. A. and Beadle, D. J. (1987) Gamma-aminobutyric acid receptors on cultured cockroach brain neurones. J. exp. Biol. 131, 231–244.

    Google Scholar 

  • Sombati, S. and Hoyle, G. (1984a) Generation of specific behaviors in a locust by local release into the neuropil of the natural neuromodulator octopamine. J. Neurobiol. 15, 481–506.

    Article  Google Scholar 

  • Sombati, S. and Hoyle, G. (1984b) Glutamatergic central nervous transmission in locusts. J. Neurobiol. 15, 507–516.

    Article  Google Scholar 

  • Suter, C. (1986) The action of octopamine and other biogenic amines on locust central neurons. Comp. Biochem. Physiol. 84C, 181–187.

    Google Scholar 

  • Suter, C. and Usherwood, P. N. R. (1985) Action of acetylcholine and antagonists on somata isolated from locust central neurons. Comp. Biochem. Physiol. 80C, 221–229.

    Article  Google Scholar 

  • Takeuchi, A. and Takeuchi, N. (1969) A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish. J. Physiol. 205, 377–391.

    Google Scholar 

  • Tareilus, E., Hanke, W. and Breer, H. (1990) Neuronal acetylcholine receptor channels from insects: a comparative electrophysiological study. J. comp. Physiol. 167, 521–526.

    Article  Google Scholar 

  • Trimmer, B. A. (1985) Serotonin and the control of salivation in the blowfly Calliphora. J. exp. Biol. 114, 307–328.

    Google Scholar 

  • Trimmer, B. A. and Weeks, J. C. (1989) Effects of nicotinic and muscarinic agents on an identified motoneurone and its direct afferent inputs in larval Manduca sexta. J. exp. Biol. 144, 303–337.

    Google Scholar 

  • Usherwood, P. N. R., Giles, D. and Suter, C. (1980) Studies of the pharmacology of insect neurons in vitro, in: Insect Neurobiology and Pesticide Action (Neurotox’79) pp. 115–128. Society of Chemical Industry, London.

    Google Scholar 

  • Usherwood, P. N. R. and Grundfest, H. (1965) Peripheral inhibition in skeletal muscle of insects. J. Neurophysiol. 28, 497–518.

    Google Scholar 

  • Vaughan, P. F. T. (1988) Amine transmitters and their associated second messenger systems, in: Comparative Invertebrate Neurochemistry, pp. 124–174. Eds G. G. Lunt and R. W. Olsen. Croom Helm, London and Sydney.

    Chapter  Google Scholar 

  • Wafford, K. A. and Sattelle, D. B. (1989) L-Glutamate receptors on the cell body membrane of an identified insect neurone. J. exp. Biol. 144, 449–462.

    Google Scholar 

  • Waldrop, B., Christensen, T. A. and Hildebrand, J. G. (1987) GABA-mediated synaptic inhibition of projection neurons in the antennal lobes of the sphinx moth, Manduca sexta. J. comp. Physiol. A 161, 23–32.

    Article  Google Scholar 

  • Waldrop, B. and Hildebrand, J. G. (1989) Physiology and pharmacology of acetylcholinergic responses of interneurons in the antennal lobes of the moth Manduca sexta. J. comp. Physiol. A 164, 433–441.

    Article  Google Scholar 

  • Walker, R. J., James, V. A., Roberts, C. J. and Kerkut, G. A. (1981) Studies on amino acid receptors of Hirudo, Helix, Limulus and Periplaneta. Adv. Physiol. Sei. 22, 161–190.

    Google Scholar 

  • Watson, A. H. D. and Burrows, M. (1987) Immunocytochemical and pharmacological evidence for GABAergic nonspiking local interneurones in the locust. J. Neurosci. 7, 1741–1761.

    Google Scholar 

  • Wright, N. J. D., Bagust, J. and Walker, R. J. (1991) An initial study of the neuropharmacology of central neurones of the scorpion Pandinus imperator. Comp. Biochem. Physiol. 99C, 85–93.

    Google Scholar 

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  1. Pharmacology Institute, University of Zürich, Gloriastrasse 32, CH-8006, Zürich, Switzerland

    Jack A. Benson

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  1. Equipe de Neurobiologie, C.N.R.S.-Université de Rennes I, Bât. 13-Complexe Univ. de Beaulieu, F-35042, Rennes Cedex, France

    Yves Pichon

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Benson, J.A. (1993). The electrophysiological pharmacology of neurotransmitter receptors on locust neuronal somata. In: Pichon, Y. (eds) Comparative Molecular Neurobiology. EXS, vol 63. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7265-2_21

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