Summary
Serotonin has long been known to function as a regulator of brain development, prior to assuming its role as a neurotransmitter in the mature brain. In addition to acting as a trophic factor on other neuronal populations, serotonin also regulates its own development. Serotonin neurons are also one of the most plastic neurotransmitter systems in the brain — that is after lesioning of terminals, the serotonin neuron has the capacity to regenerate them. In order for the phenomena of plasticity to take place, some of the trophic (or growth-promoting) molecules present during development, must be present even in the adult brain.
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© 1991 Birkhäuser Verlag Basel/Switzerland
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Whitaker-Azmitia, P.M., Azmitia, E.C. (1991). Serotonin Trophic Factors in Development, Plasticity and Aging. In: Fozard, J.R., Saxena, P.R. (eds) Serotonin: Molecular Biology, Receptors and Functional Effects. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7259-1_5
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DOI: https://doi.org/10.1007/978-3-0348-7259-1_5
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