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The Pharmacology of Neurotrophic Factors

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Pharmacological Sciences: Perspectives for Research and Therapy in the Late 1990s

Abstract

Since the early discoveries of Rita Levi-Montalcini and coworkers [1] the field of neurotrophic factors has expanded dramatically, and has become a pharmacological subject. We are facing a great number of neurotrophic factors (NTFs) with defined biological actions and conceptual therapeutic potential. Of these, the neurotrophins (the name coined for the members of the NGF gene family) and their receptors represent prototypical neurotrophic molecules (for review see [2–4]). It is our belief that future clinical neurology will exploit the knowledge evolving from current basic research for therapeutic use. This report summarizes the main achievements of basic research and relevant clinical aspects of this field, as covered by the presentations of Ted Ebendal (Uppsala, Sweden), Fred Gage (San Diego, USA) and ourselves at this Congress.

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Authors and Affiliations

  1. Department of Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada, H3G 1Y6

    A. Claudio Cuello

  2. Department of Neurochemistry, Max Planck Institute for Psychiatry, D-82152, Martinsried, Germany

    Hans Thoenen

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  1. A. Claudio Cuello
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  2. Hans Thoenen
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Editors and Affiliations

  1. Department of Pharmacology and Therapeutics Mclntyre Medical Sciences Building, McGill University, 3655 Drummond Street, Montreal, Quebec, Canada, H3G 1Y6

    A. Claudio Cuello  & Brian Collier  & 

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Claudio Cuello, A., Thoenen, H. (1995). The Pharmacology of Neurotrophic Factors. In: Cuello, A.C., Collier, B. (eds) Pharmacological Sciences: Perspectives for Research and Therapy in the Late 1990s. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7218-8_24

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  • DOI: https://doi.org/10.1007/978-3-0348-7218-8_24

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7220-1

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