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Present status of Leishmaniasis

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Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques

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Abstract

Leishmaniasis has been identified by WHO as a major and increasing public health problem. Its exact global incidence is not known but the estimated figure varies between 400 000 to 12 million cases per annum [1, 2]. Diverse species of genus Leishmania are responsible for this group of diseases but sandfly either of the genus Phlebotomus (old world) or Lutzomyia (new world) is invariably the vector. All leishmanial parasites are obligate intracellular organisms found within the macrophage phagolysosomes of the vertebrate host [3, 4]. A comprehensive review on leishmaniasis [5] was published in 1974 and the present review deals with the various developments made during the last one and a half decades in this field. The major thrust of this review is directed towards detailed understanding of the biological, biochemical and immunological aspects of the disease and also the mode of action of available antileishmanial agents.

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    Anita Mukherjee, Manju Seth & A. P. Bhaduri

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Mukherjee, A., Seth, M., Bhaduri, A.P. (1990). Present status of Leishmaniasis. In: Jucker, E. (eds) Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques, vol 34. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7128-0_15

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