Abstract
It is reasonable to assume that in cholera, as in other infectious diseases, an effective immunity is dual in nature, having both antibacterial and antitoxic components. There is little doubt that the former occurs, as evidenced by the observed protective effect of immunization with bacterial vaccines against the naturally occurring human disease [17, 25], vaccines whose nature is such that it is now known that they contain little or no enterotoxin antigen. In addition, protection against challenge infection in the guinea-pig by immunization with heat-stable 0 antigen has been described by Burrows and Ware [5].
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Burrows, W., Kaur, J. (1975). The Antibody Basis of Local Immunity to Experimental Cholera Infection in the Rabbit Ileal Loop. In: Jucker, E. (eds) Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques, vol 19. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7090-0_54
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DOI: https://doi.org/10.1007/978-3-0348-7090-0_54
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