Abstract
The characteristic paroxysmal cough associated with pertussis, is not always diagnostic of the disease as it may also be present in certain virus infections, e.g. adenovirus, respiratory syncytial virus and parainfluenza virus [1]. However, the major cause of whooping cough remains to be B. pertussis [2], Immunization with a potent pertussis vaccine in children has been shown to produce immunity but the increase in the incidence of whooping cough cases in vaccinated children [3,4] in U.K. has been ascribed to the change in the serotype of B. pertussis from 1, 2 encountered before 1962 to serotype 1,3 after 1963 [5]. In view of the varied etiology of whooping cough as well as change in the prevalent serotypes of B. pertussis, diagnosis of the disease seems important so that proper prophylactic measures can be taken as well as efficacy of pertussis vaccine assessed.
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References
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© 1975 Birkhäuser Verlag Basel
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Agarwal, K.C., Ray, M., Chitkara, N.L. (1975). Pertussis Agglutinins and Complement Fixing Antibodies in Whooping Cough. In: Jucker, E. (eds) Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques, vol 19. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7090-0_22
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DOI: https://doi.org/10.1007/978-3-0348-7090-0_22
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