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Lysostaphin: Model for a Specific Enzymatic Approach to Infectious Disease

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Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques

Abstract

It is interesting that the first antibiotic substance, documented by Emmerich and Löw [1], was an enzyme, pyocyanase, produced by Pseudomonas aeruginosa. Fleming in 1922 isolated a bacteriolytic enzyme from egg white which lysed cells of Micrococcus lysodeikticus and of several other gram-positive bacteria [2]. Other bacteriolytic enzymes were subsequently reported from Bacillus mesentericus [3], P. fluorescens [4] and Serratia marcescens [5].

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Authors and Affiliations

  1. Department of Biochemistry, Mead Johnson Research Center, Evansville, Indiana, 47721, USA

    Walter A. Zygmunt & Peter A. Tavormina

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  1. Walter A. Zygmunt
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  2. Peter A. Tavormina
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  1. Basel, Switzerland

    Ernst Jucker

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Zygmunt, W.A., Tavormina, P.A. (1972). Lysostaphin: Model for a Specific Enzymatic Approach to Infectious Disease. In: Jucker, E. (eds) Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques, vol 16. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7081-8_7

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  • DOI: https://doi.org/10.1007/978-3-0348-7081-8_7

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7083-2

  • Online ISBN: 978-3-0348-7081-8

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