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Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques pp 11–58Cite as

Reduction of drug action by drug combination

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Abstract

Combination of drugs may imply combination of two compounds in one formulation, application of two drugs in separate formulations at the same time, and application of two drugs with a certain time interval. No doubt such combinations may bring about complications because of the various possibilities of interaction between the drugs combined. A consequence of the interaction may be an enhancement or a reduction in the action. Drug interactions are manifold and their therapeutic consequences form a topic of high actuality [21a, 21b, 54, 56, 69, 70, 71, 80, 80a, 83a, 101, 102, 127a, 127b].

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  1. Department of Pharmacology, University of Nijmegen, The Netherlands

    E. J. Ariëns

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    Ernst Jucker

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Ariëns, E.J. (1970). Reduction of drug action by drug combination. In: Jucker, E. (eds) Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des Recherches Pharmaceutiques, vol 14. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7075-7_1

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