Skip to main content

Abstract

Interest in the study of indole-containing compounds in biological systems has increased dramatically over the past decade. Tangible evidence for this interest is the fact that this chapter has been preceded by two earlier ones in the second and third volumes of this series. These reviews have discussed, respectively, the naturally occurring indoles isolated from plant and animal sources [35]1) and the effects of serotonin and other tryptamines on biological systems [56]. The latter chapter contains over 1300 references to papers published in the preceding six years, clearly pointing out the remarkable variety of target organs which respond to members of this class of compounds.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. R. A. Abramovitch and D. Shapiro, Chem. and Ind. (London) 1955, 1255.

    Google Scholar 

  2. C. Alberti, Gazz. chim. ital. 77 (1947), 398.

    Google Scholar 

  3. C. Y. Almond and F. G. Mann, J. Chem. Soc. 1952, 1870.

    Google Scholar 

  4. A. F. Ames, D. E. Ames, C. R. Coyne, T. F. Grey, I. M. Lockhart, and R. S. Ralph, J. Chem. Soc. 1959, 3388.

    Google Scholar 

  5. D. E. Ames, R. E. Bowman, D. D. Evans, and W. A. Jones, J. Chem. Soc. 1956, 1984.

    Google Scholar 

  6. D. G. Anger, The Upjohn Company, unpublished results.

    Google Scholar 

  7. W. C. Anthony, The Upjohn Company, unpublished results.

    Google Scholar 

  8. W. C. Anthony, J. Org. Chem. 25 (1960), 2050.

    Article  Google Scholar 

  9. W. C. Anthony, J. Org. Chem. 25 (1960), 2049; M. R. De maheas, Bull. soc. chim. France 1962, 1989.

    Article  Google Scholar 

  10. O. H. Arnold and G. Hoffmann, Wien. Ztschr. Nervenh. 13 (1957), 438.

    Google Scholar 

  11. B. Asero, V. Colo, V. Erspamer, and A. Vercellone, Ann. 576 (1952), 69.

    Google Scholar 

  12. A. S. F. Ash and W. R. Wragg, J. Chem. Soc. 1958, 3887.

    Google Scholar 

  13. J. Axelrod, J. Pharmacol. Exp. Therap. 138 (1962), 28.

    Google Scholar 

  14. J. Axelrod and H. Weissbach, Science 131 (1960), 1312.

    Article  Google Scholar 

  15. J. Axelrod and H. Weissbach, J. Biol. Chem. 236 (1961), 211.

    Google Scholar 

  16. R. B. Barlow and I. Khan, Brit. J. Pharmacol. 14 (1959), 99.

    Google Scholar 

  17. J. A. Barltrop and D. A. H. Taylor, J. Chem. Soc. 1954, 3403.

    Google Scholar 

  18. G. Bernini, Ann. chim. (Rome) 43 (1953), 559.

    Google Scholar 

  19. G. Berti and A. Da Settimo, Gazz. chim. ital. 90 (1960), 525.

    Google Scholar 

  20. K. Bhagvat, H. Blaschko, and D. Richter, Biochem. J. 33 (1939), 1338.

    Google Scholar 

  21. J. H. Birkinshaw and C. E. Stickings, Progress in the Chemistry of Organic Natural Products, Ed. L. Zechmeister, Vol. 20 (Springer-Verlag, Vienna 1962), p. 17.

    Google Scholar 

  22. R. C. Blume and H. G. Lindwall, J. Org. Chem. 10 (1945), 255.

    Article  Google Scholar 

  23. D. F. Bogdanski, A. Pletscher, B. B. Brodie, and S. Udenfriend, J. Pharmacol. Exp. Therap. 117 (1956), 82.

    Google Scholar 

  24. F. Bohlmann, Ber. 89 (1956), 2191.

    Article  Google Scholar 

  25. Z. Böszorményi and S. Szara, J. Mental Sci. 104 (1958), 445.

    Google Scholar 

  26. B. Brodie, J. Axelrod, P. A. Shore, and S. Udenfriend, J. Biol. Chem. 208 (1954), 741.

    Google Scholar 

  27. J. B. Brown, H. B. Henbest, and E. R. H. Jones, J. Chem. Soc. 1952, 3172.

    Google Scholar 

  28. J. Brüesch and P. Karrer, Helv. Chim. Acta 38 (1955), 905.

    Article  Google Scholar 

  29. R. J. Brunton, F. K. Drayson, S. G. P. Plant, and M. L. Tomlison, J. Chem. Soc. 1956, 4783.

    Google Scholar 

  30. F. V. Brutcher and W. D. Vanderwerff, J. Org. Chem. 23, 146 (1958).

    Article  Google Scholar 

  31. R. Bucourt, J. Valls, and R. Joly, U.S. Patent 2920080.

    Google Scholar 

  32. F. M. Bumpus and I. H. Page, J. Biol. Chem. 212 (1955), 111.

    Google Scholar 

  33. H. Burton and J. L. Stoves, J. Chem. Soc. 1937, 1726.

    Google Scholar 

  34. A. Buzas, C. Hoffmann, and G. Régnier, Bull. soc. chim. France 1960, 643.

    Google Scholar 

  35. A. Cerletti, Progress in Drug Research, Ed. E. Jucker, Vol. 2 (Birkhäuser-Verlag, Basel 1960), p. 227.

    Google Scholar 

  36. C. T. Clark, H. Weissbach, and S. Udenfriend, J. Biol. Chem. 210 (1954), 139.

    Google Scholar 

  37. S. Coffey and J. Van Alphen, Chemistry of Carbon Compounds, Ed. E. H. Rodd, Vol. IIIB (Elsevier Publishing Co., New York 1956), p. 1376.

    Google Scholar 

  38. A. H. Conney, C. Davison, R. Gastel, and J. J. Burns, J. Pharmacol. Exp. Therap. 130 (1960), 1.

    Google Scholar 

  39. N. D. Connor, O. F. Swoap, and H. D. Webster, The Upjohn Company, unpublished results.

    Google Scholar 

  40. J. T. Correll and A. W. Neff, The Upjohn Company, unpublished results.

    Google Scholar 

  41. J. W. Daly and B. Witkop, J. Org. Chem. 27 (1962), 4104.

    Article  Google Scholar 

  42. J. P. Da Vanzo, The Upjohn Company, unpublished results.

    Google Scholar 

  43. R. S. De Ropp, Drugs and Mind (St. Martin’s Press Inc., New York 1957).

    Google Scholar 

  44. W. Deulofeu, Fortschritte der Chemie Organischer Naturstoffe, Ed. L. Zechmeister, Vol. 5 (Springer-Verlag, Vienna 1948), p. 257–261.

    Google Scholar 

  45. P. B. Dews, Brit. J. Pharmacol 8 (1953), 46.

    Google Scholar 

  46. O. Diels and K. Alder, Ann. 490 (1931), 277.

    Google Scholar 

  47. A. Dietz, The Upjohn Company, unpublished results.

    Google Scholar 

  48. H. Von Dobeneck, W. Lehnerer, and G. Maresch, Z. physiol. Chem., Hoppe-Seyler’s 304 (1956), 26.

    Article  Google Scholar 

  49. I. B. Douglass and B. S. Farah, J. Org. Chem. 26 (1961), 351.

    Article  Google Scholar 

  50. D. F. Downing, Quart. Rev. (London) 16 (1962), 133.

    Article  Google Scholar 

  51. F. S. Eberts and E. G. Daniels, The Upjohn Company, unpublished results.

    Google Scholar 

  52. F. S. Eberts and E. G. Daniels, Federation Proc. 21 (1962), 180.

    Google Scholar 

  53. A. Ek and B. Witkop, J. Am. Chem. Soc. 76 (1954), 5579.

    Article  Google Scholar 

  54. H. Erdtman and A. Jönsson, Acta Chem. Scand. 8 (1954), 119.

    Article  Google Scholar 

  55. V. Erspamer, Il Sistema Cellulare Enterocromaffine E. L’Enteramine, Recondicinti Scientifici Farmitalia, Vol. 7 (1954).

    Google Scholar 

  56. V. Erspamer, Progress in Drug Research, Ed. E. Jucker, Vol. 3 (Interscience, New York 1961), p. 151.

    Google Scholar 

  57. V. Erspamer, Progress in Drug Research, Ed. E. Jucker, Vol. 3 (Interscience, New York 1961), p. 269.

    Google Scholar 

  58. H. D. Fabing and J. R. Hawkins, Science 123 (1956), 886.

    Article  Google Scholar 

  59. G. Farrell, Circulation 21 (1960), 1009.

    Google Scholar 

  60. G. Farrell and W. M. McIsaac, Arch. Biochem. Biophys. 94 (1961), 543.

    Article  Google Scholar 

  61. G. Farrell and W. M. McIsaac, personal communication.

    Google Scholar 

  62. W. R. Fearon and W. A. Boggust, Biochem. J. 46 (1950), 62.

    Google Scholar 

  63. A. Fischer, Planta 43 (1954), 288.

    Article  Google Scholar 

  64. E. Fischer, T. A. Fernandez Lagravere, A. J. Vazquez, and A. O. Di Stefano, J. Nervous Mental Disease 133 (1961), 441.

    Article  Google Scholar 

  65. M. S. Fish, N. M. Johnson, and E. C. Horning, J. Am. Chem. Soc. 77 (1955), 5892.

    Article  Google Scholar 

  66. M. S. Fish, N. M. Johnson, and E. C. Horning, J. Am. Chem. Soc. 78 (1956), 3668.

    Article  Google Scholar 

  67. M. S. Fish, C. C. Sweeley, and E. C. Horning, Chem. and Ind. (London) 1956, 24.

    Google Scholar 

  68. R. A. Freedland, I. M. Wadzinski, and H. A. Waisman, Biochem. Biophys. Res. Commun. 5 (1961), 94.

    Article  Google Scholar 

  69. R. A. Freedland, I. M. Wadzinski, and H. A. Waisman, Biochem. Biophys. Res. Commun. 6 (1961), 227.

    Article  Google Scholar 

  70. J. P. Freeman, J. Org. Chem. 26 (1961), 3507.

    Article  Google Scholar 

  71. J. P. Freeman and M. F. Hawthorne, J. Am. Chem. Soc. 78 (1956), 3366.

    Article  Google Scholar 

  72. W. A. Freyburger, The Upjohn Company, unpublished results.

    Google Scholar 

  73. W. A. Freyburger and B. E. Graham, The Upjohn Company, unpublished results.

    Google Scholar 

  74. D. W. Fuhlhage and C. A. Vanderwerf, J. Am. Chem. Soc. 80 (1958), 6249.

    Article  Google Scholar 

  75. R. F. Furchgott and S. Bhadrakom, J. Pharmacol. Exp. Therap. 108 (1953), 129.

    Google Scholar 

  76. N. G. Gaylord, Experientia 10 (1954), 351.

    Article  Google Scholar 

  77. N. G. Gaylord, Reduction With Complex Metal Hydrides (Interscience, New York 1956), p. 981.

    Google Scholar 

  78. K. F. Gey and A. Pletscher, Brit. J. Pharmacol. 19 (1962), 161.

    Google Scholar 

  79. U. Ghatak, N. N. Saha, and P. C. Dutta, J. Am. Chem. Soc. 79 (1957), 4487.

    Article  Google Scholar 

  80. H. Gooder and F. C. Happold, Biochem. J. 55 (1953), XXXII.

    Google Scholar 

  81. M. Goto, T. Noguchi, and T. Watanabe, Yakugaku Zasshi 78 (1958), 464; through Chem. Abstr. 52 (1958), 1482.

    Google Scholar 

  82. W. M. Govier, B. G. Howes, and A. J. Gibbons, Science 118 (1953), 596.

    Article  Google Scholar 

  83. B. E. Graham, The Upjohn Company, unpublished results.

    Google Scholar 

  84. J. B. Greenberg, A. W. Galston, K. N. F. Shaw, and M. D. Armstrong, Science 125 (1957), 992.

    Article  Google Scholar 

  85. M. E. Greig, The Upjohn Company, unpublished results.

    Google Scholar 

  86. M. E. Greig, D. L. Brown, and A. J. Gibbons, The Upjohn Company, unpublished results.

    Google Scholar 

  87. M. E. Greig and A. J. Gibbons, Arch. intern. pharmacol. 136 (1962), 147.

    Google Scholar 

  88. M. E. Greig, A. J. Gibbons, R. A. Walk, D. L. Brown, and L. J. Peterson, The Upjohn Company, unpublished results.

    Google Scholar 

  89. M. E. Greig, H. H. Keasling, and R. J. Matthews, The Upjohn Company, unpublished results.

    Google Scholar 

  90. M. E. Greig, R. J. Matthews, and W. A. Freyburger, Psychosomatic Medicine, Ed. J. H. Nodine and J. H. Moyer (Lea and Febiger, Philadelphia 1962), p. 643.

    Google Scholar 

  91. M. E. Greig, P. H. Seay, and W. A. Freyburger, J. Neuropsychiat. 2, Suppl. 1, (1961), S. 131.

    Google Scholar 

  92. M. E. Greig, R. A. Walk, and A. J. Gibbons, J. Pharmacol. Exp. Therap. 127 (1959), 110.

    Google Scholar 

  93. C. A. Grob and J. Voltz, Helv. Chim. Acta 33 (1950), 1796.

    Article  Google Scholar 

  94. C. A. Grob and O. Weissbach, Helv. Chim. Acta 44 (1961), 1736.

    Article  Google Scholar 

  95. H. M. Grotta, C. J. Riggle, and A. E. Bearse, J. Org. Chem. 26 (1961), 1509.

    Article  Google Scholar 

  96. A. N. Hall, J. A. Leeson, H. N. Rydon, and J. C. Tweddle, Biochem. J. 74 (1960), 209.

    Google Scholar 

  97. K. E. Hamlin and F. E. Fischer, J. Am. Chem. Soc. 73 (1951), 5007.

    Article  Google Scholar 

  98. J. Harley-Mason, Chem. and Ind. (London) 1951, 886.

    Google Scholar 

  99. J. Harley-Mason, J. Chem. Soc. 1952, 2433.

    Google Scholar 

  100. J. Harley-Mason and J. D. Bu’lock, Biochem. J. 51 (1952), 430.

    Google Scholar 

  101. J. Harley-Mason and A. H. Jackson, J. Chem. Soc. 1954, 1165.

    Google Scholar 

  102. R. V. Heinzelman, W. C. Anthony, D. A. Lyttle, and J. Szmuszkovicz, J. Org. Chem. 25 (1960), 1548.

    Article  Google Scholar 

  103. J. B. Hester, The Upjohn Company, unpublished results.

    Google Scholar 

  104. J. B. Hester, M. E. Greig, W. C. Anthony, R. V. Heinzelman, and J. Szmuszkovicz, The Upjohn Company, unpublished results.

    Google Scholar 

  105. R. K. Hill, J. Org. Chem. 27 (1962), 29.

    Article  Google Scholar 

  106. H. E. Himwich, J. Neuropsychiat. 2, Suppl. 1 (1961), S 136.

    Google Scholar 

  107. F. A. Hochstein and A. M. Paradies, J. Am. Chem. Soc. 79 (1957), 5735.

    Article  Google Scholar 

  108. A. Hofmann, R. Heim, A. Brack, and H. Kobel, Experientia 14 (1958), 107.

    Article  Google Scholar 

  109. D. O. Holland and J. H. C. Nayler, J. Chem. Soc. 1953, 280.

    Google Scholar 

  110. Huang-Minlon, J. Am. Chem. Soc. 68 (1946), 2487.

    Article  Google Scholar 

  111. R. E. Ireland, Chem. and Ind. (London) 1958, 979.

    Google Scholar 

  112. J. R. Johnson, R. B. Hasbrouck, J. D. Dutcher, and W. F. Bruce, J. Am. Chem. Soc. 67, (1945) 423.

    Article  Google Scholar 

  113. R. Justoni and R. Pessina, Farmaco (Pavia), Ed. sci. 10 (1955), 356.

    Google Scholar 

  114. A. Kalir and S. Szara, Federation Proc. 21 (1962), 337.

    Google Scholar 

  115. H. H. Keasling, The Upjohn Company, unpublished results.

    Google Scholar 

  116. H. H. Keasling and W. Veldkamp, The Upjohn Company, unpublished results.

    Google Scholar 

  117. S. Kessar and M. C. Kloetzel, J. Org. Chem. 27 (1962), 1314.

    Article  Google Scholar 

  118. M. S. Kharasch and O. Reinmuth, Grignard Reactions of Non-metallic Substances (Prentice Hall, New York 1954), p. 189.

    Google Scholar 

  119. M. S. Kharasch and O. Reinmuth, Grignard Reactions of Non-metallic Substances (Prentice Hall, New York 1954), p. 870.

    Google Scholar 

  120. A. W. Kimball, W. T. Burnett, and D. G. Doherty, Radiation Res. 7 (1957), 1.

    Article  Google Scholar 

  121. I. J. Kopin, C. M. B. Pare, J. Axelrod, and H. Weissbach, J. Biol. Chem. 236 (1961), 3072.

    Google Scholar 

  122. M. Kunori, Nippon Kagaku Zasshi 80 (1959), 407; through Chem. Abstr. 55 (1961), 5457.

    Article  Google Scholar 

  123. M. Kunori, Nippon Kagaku Zasshi 80 (1959), 409; through Chem. Abstr. 55 (1961), 5458.

    Article  Google Scholar 

  124. S. Kveder and W. M. McIsaac, J. Biol. Chem. 236 (1961), 3214.

    Google Scholar 

  125. E. J. Larson, The Upjohn Company, unpublished results.

    Google Scholar 

  126. E. Leete and L. Marion, Can. J. Chem. 31 (1953), 775.

    Article  Google Scholar 

  127. A. B. Lerner and J. D. Case, J. Invest. Dermatol. 32 (1959), 211.

    Article  Google Scholar 

  128. A. B. Lerner and J. D. Case, Federation Proc. 19 (1960), 590.

    Google Scholar 

  129. A. B. Lerner, J. D. Case, and R. V. Heinzelman, J. Am. Chem. Soc. 81 (1959), 6084.

    Article  Google Scholar 

  130. A. B. Lerner, J. D. Case, W. Mori, and M. R. Wright, Nature 183 (1959), 1821.

    Article  Google Scholar 

  131. A. B. Lerner, J. D. Case, Y. Takahashi, T. H. Lee, and W. Mori, J. Am. Chem. Soc. 80 (1958), 2587.

    Article  Google Scholar 

  132. S. V. Liebermann and E. C. Wagner, J. Org. Chem. 14 (1949), 1001.

    Article  Google Scholar 

  133. R. Majima and M. Kotake, Ber. 58 (1925), 2037.

    Google Scholar 

  134. F. Märki, A. V. Robertson, and B. Witkop, J. Am. Chem. Soc. 83 (1961), 3341.

    Article  Google Scholar 

  135. R. J. Matthews, B. J. Roberts, and P. K. Adkins, J. Neuropsychiat. 2, Suppl. 1 (1961), S 151.

    Google Scholar 

  136. W. M. McIsaac, Postgrad. Med. 30 (1961), 111.

    Google Scholar 

  137. W. M. McIsaac, Biochim. Biophys. Acta 52 (1961), 607.

    Article  Google Scholar 

  138. W. M. McIsaac, P. A. Khairallah, and I. H. Page, Science 134 (1961), 674.

    Article  Google Scholar 

  139. W. M. McIsaac and I. H. Page, J. Biol. Chem. 234 (1959), 858.

    Google Scholar 

  140. L. J. Meduna, J. Neuropsychiat. 2, Suppl. 1 (1961).

    Google Scholar 

  141. R. B. Moffett and B. D. Aspergren, J. Am. Chem. Soc. 82 (1960), 1600.

    Article  Google Scholar 

  142. R. B. Moffett, P. H. Seay, and W. B. Reid, J. Med. Pharm. Chem. 2 (1960), 179.

    Article  Google Scholar 

  143. J. A. Moore and M. Rahm, J. Org. Chem. 26 (1961), 1109.

    Article  Google Scholar 

  144. N. C. Moran, G. P. Quinn, and W. M. Butler, J. Pharmacol. Exp. Therap. 125 (1959), 85.

    Google Scholar 

  145. H. B. Murphee, E. H. Jenney, and C. C. Pfeiffer, The Pharmacologist 2 (1960), 64.

    Google Scholar 

  146. W. E. Noland and C. F. Hammer, J. Org. Chem. 25 (1960), 1536.

    Article  Google Scholar 

  147. W. E. Noland and P. J. Hartman, J. Am. Chem. Soc. 76 (1954), 3227.

    Article  Google Scholar 

  148. W. E. Noland and R. A. Hovden, J. Org. Chem. 24 (1959), 894.

    Article  Google Scholar 

  149. W. E. Noland and J. E. Johnson, Tetrahedron Letters 14 (1962), 589.

    Article  Google Scholar 

  150. W. E. Noland, C. G. Richards, H. S. Desai, and M. R. Venkiteswaran, J. Org. Chem. 26 (1961), 4254.

    Article  Google Scholar 

  151. W. E. Noland and M. R. Venkiteswaran, J. Org. Chem. 26 (1961), 4263.

    Article  Google Scholar 

  152. B. Oddo and L. Sessa, Gazz. chim. ital. 41 (1911), 234.

    Google Scholar 

  153. Y. G. Perron and W. F. Minor, J. Org. Chem. 24 (1959), 1165.

    Article  Google Scholar 

  154. S. Pietra and G. Tacconi, Farmaco (Pavia), Ed. sci. 13, (1958) 893

    Google Scholar 

  155. A. G. Terzian, R. R. Safrasbekian, R. S. Sukasian, and G. T. Tatevosian, Experientia 17, (1961) 493.

    Article  Google Scholar 

  156. S. Piltra, Farmaco (Pavia), Ed. sci. 13 (1958), 75.

    Google Scholar 

  157. H. Plieninger and I. Nógrádi, Ber. 88 (1955), 1961.

    Article  Google Scholar 

  158. Ramart-Lucas and M. Roch, Compt. rend. 232 (1951), 843.

    Google Scholar 

  159. M. M. Rapport, J. Biol. Chem. 180 (1949), 961.

    Google Scholar 

  160. W. Reppe and H. Ufer, German Patent 698273.

    Google Scholar 

  161. T. R. Robie, J. Neuropsychiat. 2, Suppl. 7 (1961), S. 31.

    Google Scholar 

  162. B. Robinson, G. F. Smith, A. H. Jackson, D. Shaw, B. Frydman, and V. Deulofeu, Proc. Chem. Soc. 1961, 310.

    Google Scholar 

  163. R. Rodnight, Biochem. J. 64 (1956), 621.

    Google Scholar 

  164. N. Roh and W. Wolff, German Patent 641597.

    Google Scholar 

  165. A. Sai-Hal’asz, G. Brunecker, and I. Szara, Psychiat. et Neurol. 135 (1958), 285.

    Article  Google Scholar 

  166. J. E. Saxton, J. Chem. Soc. 1952, 3592.

    Google Scholar 

  167. P. H. Seay, The Upjohn Company, unpublished results.

    Google Scholar 

  168. E. Shaw, J. Am. Chem. Soc. 76 (1954), 1384.

    Article  Google Scholar 

  169. E. Shaw and D. W. Wooley, J. Am. Chem. Soc. 75 (1953), 1877.

    Article  Google Scholar 

  170. J. C. Sheehan, M. Goodman, and G. P. Hess, J. Am. Chem. Soc. 78 (1956), 1367.

    Article  Google Scholar 

  171. G. F. Smith, J. Chem. Soc. 1954, 3842.

    Google Scholar 

  172. H. R. Snyder and L. Katz, J. Am. Chem. Soc. 69 (1947), 3140.

    Article  Google Scholar 

  173. H. R. Snyder and J. A. MacDonald, J. Am. Chem. Soc. 77 (1955), 1257.

    Article  Google Scholar 

  174. H. R. Snyder, E. P. Merica, C. G. Force, and E. G. White, J. Am. Chem. Soc. 80 (1958), 4622.

    Article  Google Scholar 

  175. M. E. Speeter, Abstracts of the Fifth National Medicinal Chemistry Symposium, American Chemical Society (East Lansing, Michigan, June 1956), p. 39.

    Google Scholar 

  176. M. E. Speeter, U.S. Patent 2692882.

    Google Scholar 

  177. M. E. Speeter and W. C. Anthony, The Upjohn Company, unpublished results.

    Google Scholar 

  178. M. E. Speeter and W. C. Anthony, J. Am. Chem. Soc. 76 (1954), 6208.

    Article  Google Scholar 

  179. M. E. Speeter, R. V. Heinzelman, and D. I. Weisblat, J. Am. Chem. Soc. 73 (1951), 5514.

    Article  Google Scholar 

  180. V. L. Stromberg, J. Am. Chem. Soc. 76 (1954), 1707.

    Article  Google Scholar 

  181. S. Swaminathan, S. Ranganathan, and S. Sulochana, J. Org. Chem. 23 (1958), 707, and References therein.

    Article  Google Scholar 

  182. S. Szara, Experientia 12 (1956), 441.

    Article  Google Scholar 

  183. S. Szara and J. Axelrod, Experientia 15 (1959), 216.

    Article  Google Scholar 

  184. S. Szara and E. Hearst, Ann. N.Y. Acad. Sci. 96 (1962), 134.

    Article  Google Scholar 

  185. J. Szmuszkovicz, The Upjohn Company, unpublished results.

    Google Scholar 

  186. J. Szmuszkovicz, J. Am. Chem. Soc. 79 (1957), 2819.

    Article  Google Scholar 

  187. J. Szmuszkovicz, J. Am. Chem. Soc. 80 (1958), 3782.

    Article  Google Scholar 

  188. J. Szmuszkovicz, J. Am. Chem. Soc. 82 (1960), 1180.

    Article  Google Scholar 

  189. J. Szmuszkovicz, J. Org. Chem. 27 (1962), 511.

    Article  Google Scholar 

  190. J. Szmuszkovicz, J. Org. Chem. 27 (1962), 515.

    Article  Google Scholar 

  191. J. Szmuszkovicz, J. Org. Chem. 27 (1962), 1582.

    Article  Google Scholar 

  192. J. Szmuszkovicz and W. C. Anthony, The Upjohn Company, unpublished results.

    Google Scholar 

  193. J. Szmuszkovicz, W. C. Anthony, and R. V. Heinzelman, J. Org. Chem. 25 (1960), 857.

    Article  Google Scholar 

  194. J. Szmuszkovicz and R. C. Thomas, J. Org. Chem. 26 (1961), 960.

    Article  Google Scholar 

  195. A. P. Terentyev, A. N. Kost, and V. A. Smit, J. Gen. Chem. (USSR) in English translation 25 (1955), 1905.

    Google Scholar 

  196. Tiffeneau and Dorlencourt, Compt. rend. 143 (1906), 126.

    Google Scholar 

  197. G. Tsatsas, Compt. rend. 235 (1952), 175.

    Google Scholar 

  198. W. J. Turner and S. Merlis, A.M.A. Arch. Neurol. Psychiat. 81 (1959), 121.

    Google Scholar 

  199. F. C. Uhle, J. Am. Chem. Soc. 71 (1949), 761.

    Article  Google Scholar 

  200. F. C. Uhle, C. G. Vernick, and G. L. Schmir, J. Am. Chem. Soc. 77 (1955), 3334.

    Article  Google Scholar 

  201. J. R. Vane, H. O. J. Collier, S. J. Corne, E. Marley, and P. B. Bradley, Nature 191 (1961), 1068.

    Article  Google Scholar 

  202. A. B. Varley, The Upjohn Company, unpublished clinical studies.

    Google Scholar 

  203. T. Verhave, J. E. Owen, and E. B. Robbins, Arch. intern. Pharmacodynamie 116 (1958), 45.

    Google Scholar 

  204. R. Voigt, Pharmazie 17 (1962), 318.

    Google Scholar 

  205. G. N. Walker, J. Am. Chem. Soc. 77 (1955), 3844.

    Article  Google Scholar 

  206. G. N. Walker and B. N. Weaver, J. Org. Chem. 26 (1961), 4441.

    Article  Google Scholar 

  207. E. Wegler and H. Binder, Arch. Pharm. 275 (1937), 506.

    Article  Google Scholar 

  208. H. Weissbach, B. G. Redfield, and J. Axelrod, Biochim. Biophys. Acta 43 (1960), 352.

    Article  Google Scholar 

  209. E. Wenkert, J. H. Udelhofen, and N. K. Bhattacharyya, J. Am. Chem. Soc. 81 (1959), 3763.

    Article  Google Scholar 

  210. T. Wieland, O. Weiberg, E. Fischer, and G. Hörlein, Ann. 587 (1954), 146.

    Google Scholar 

  211. H. Wieland and T. Wieland, Ann. 528 (1937), 234.

    Google Scholar 

  212. R. E. Willette, The Upjohn Company, unpublished results.

    Google Scholar 

  213. B. Witkop, J. Am. Chem. Soc. 78 (1956), 2873.

    Article  Google Scholar 

  214. R. B. Woodward, F. E. Bader, H. Bickel, A. J. Frey, and R. W. Kierstead, Tetrahedron 2 (1958), 1.

    Article  Google Scholar 

  215. C. Yanofsky, J. Biol. Chem. 223 (1956), 171.

    Google Scholar 

  216. C. Yanofsky, Biochim. Biophys. Acta 20 (1956), 438.

    Article  Google Scholar 

  217. H. C. Y. Yen, C. A. Day, and E. B. Sigg, The Pharmacologist 4 (1962), 173.

    Google Scholar 

  218. E. H. P. Young, J. Chem. Soc. 1958, 3493.

    Google Scholar 

  219. E. W. Young, The Upjohn Company, unpublished clinical studies.

    Google Scholar 

  220. G. A. Youngdale, The Upjohn Company, unpublished results.

    Google Scholar 

  221. G. A. Youngdale, W. C. Anthony, R. V. Heinzelman, and J. Szmuszkovicz, The Upjohn Company, unpublished results.

    Google Scholar 

  222. H. E. Zaugg, R. J. Michaels, and R. W. De Net, J. Org. Chem. 23 (1958), 847, and Reference 3 cited therein.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1963 Birkhäuser Verlag Basel

About this chapter

Cite this chapter

Heinzelman, R.V., Szmuszkovicz, J. (1963). Recent Studies in the Field of Indole Compounds. In: Jucker, E. (eds) Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des Recherches Pharmaceutiques, vol 6. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7050-4_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-7050-4_2

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7052-8

  • Online ISBN: 978-3-0348-7050-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics