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Recent Research in the Field of 5-Hydroxytryptamine and Related Indolealkylamines

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Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des Recherches Pharmaceutiques

Part of the book series: Progress in Drug Research ((PDR,volume 3))

Abstract

This review article is intended to give an account of the progress of research in the field of 5-hydroxytryptamine (5-HT) and related indolealkylamines in the last 6 to 7 years. Approximately 2000 papers have appeared on the subject during this period. We shall endeavour to review here the best from the more important ones. The reader is referred to previous review articles for papers preceding 1955.

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Abbreviations

ACTH:

Adrenocorticotropic Hormone

ATP:

Adenosine-triphosphate

BAB:

l-Benzyl-2-methyl-5-methoxy-N, N-dimethyl-tryptamine (benzylanalogue of bufotenine)

BAS:

1-Benzyl-2-methyl-5-methoxytryptamine (benzylanalogue of serotonin)

BOL:

2-Bromo-lysergic acid diethylamide

CNS:

Central Nervous System

DCA:

Desoxycorticosterone acetate

DOPA:

3, 4-Dihydroxy-phenylalanine

DPN:

Oxidized diphosphopyridine nucleotide

EC:

Enterochromaffin Cell(s)

EDTA:

(Ethylenedinitrilo) tetraacetic acid tetrasodium salt

EEG:

Electroencephalogram

GABA:

γ-Amino-butyric acid

GFR:

Glomerular Filtration Rate

5-HIAA:

5-Hydroxyindole acetic acid

5-HIAA1:

5-Hydroxyindoleacetaldehyde

5-HT:

5-Hydroxytryptamine

5-HTP:

DL-5-Hydroxytryptophan

4-HIAA:

4-Hydroxyindole acetic acid

4-HT:

4-Hydroxytryptamine

4-HTP:

DL-4-Hydroxytryptophan

IAA:

Indoleacetic acid

LSD:

D-Lysergic acid diethylamide

LSM:

D-Lysergic acid morpholide

MAO:

Monoaminoxydase

MBL:

1-Methyl-2-bromo-lysergic acid diethylamide

MLD:

1-Methyl-lysergic acid diethylamide

MSH:

Melanocyte-stimulating Hormone

PIH:

β-Phenylisopropylhydrazine

PAS:

Paraaminosalicylic acid

RPF:

Renal Plasma Flow

STH:

Somatotropic hormone

T:

Tryptamine

TP:

Tryptophan

TPNH:

Reduced triphosphopyridine nucleotide

UML:

1-Methyl-D-lysergic acid butanolamide

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  1. Istituto di Farmacologia, Università di Parma, Italy

    V. Erspamer

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  1. Pharmazeutisch-chemisches Laboratorium, Sandoz AG., Basel, Switzerland

    Ernst Jucker

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Erspamer, V. (1961). Recent Research in the Field of 5-Hydroxytryptamine and Related Indolealkylamines. In: Jucker, E. (eds) Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des Recherches Pharmaceutiques. Progress in Drug Research, vol 3. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7041-2_3

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