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Retroviral Vectors

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Gene Therapy

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Summary

Retroviral vectors represent the most widely used vector system for gene therapy. They are currently in the clinic for treatment of a wide variety of diseases, from cancer to virus infection to arthritis. Although the current vectors have worked efficiently for gene transfer in the initial trials, it is likely that modifications of both the vector and packaging lines should result in even higher titer, targetable viruses with elevated and/or regulated gene expression. Thus, it is likely that retroviral vectors will continue to be the vector of choice for many gene therapy applications.

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Authors
  1. P. D. Robbins
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Editors and Affiliations

  1. Max-Delbrück-Centrum für molekulare Medizin, Robert-Rössle-Strasse 10, D-13122, Berlin-Buch, Germany

    Thomas Blankenstein

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© 1999 Birkhäuser Verlag Basel

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Robbins, P.D. (1999). Retroviral Vectors. In: Blankenstein, T. (eds) Gene Therapy. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7011-5_2

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  • DOI: https://doi.org/10.1007/978-3-0348-7011-5_2

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7013-9

  • Online ISBN: 978-3-0348-7011-5

  • eBook Packages: Springer Book Archive

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