Abstract
When the heart of a 7-day-old chick embryo is dissociated into its component cells, a majority of those cells (50–60%), completely isolated from contact with neighbors, are capable of spontaneous rhythmic activity when maintained under suitable in vitro culture conditions1*. Any such single isolated cell which is seen to beat must be initiating its own activity, and may thus be defined as a pacemaker2. Moreover, such a cell, within 5–30 min after coming into contact with a more slowly beating neighbor, may cause that neighbor to beat in synchrony with it.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
R. L. de Haan, Devel. Biol. 16, 216 (1967).
R. L. de Haan, Factors Influencing Myocardial Contractility (Ed. R. D. Tanz, F. Kavaler and J. Roberts; Academic Press, New York 1967), p. 217.
R. L. de Haan and S. H. Gottlieb, J. gen. Physiol. 52, 643 (1968).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1969 Springer Basel AG
About this chapter
Cite this chapter
DeHaan, R.L. (1969). Electrical Recording from Embryonic Heart Cells Isolated in Tissue Culture. In: McCann, F.V. (eds) Comparative Physiology of the Heart: Current Trends. Experientia Supplementum. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-6800-6_14
Download citation
DOI: https://doi.org/10.1007/978-3-0348-6800-6_14
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-6788-7
Online ISBN: 978-3-0348-6800-6
eBook Packages: Springer Book Archive