Abstract
The determination of the amino acid sequences of metallothioneins has been undertaken with the aim of obtaining information on 1) the distribution of metal-liganding cysteinyl residues in the polypeptide chain, 2) the mode of metal-protein interaction, 3) the relationship between chemical structure and metal-ion selectivity, 4) the structural basis of chromatographic polymorphism, 5) the identity or difference of metallothioneins from different organs, and 6) the evolution of metallothioneins. The answers to these questions were also expected to provide some further clues for the understanding of the physiological function of metallothionein.
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Kojima, Y., Berger, C., Kägi, J.H.R. (1979). The Amino Acid Sequence of Equine Metallothioneins. In: Kägi, J.H.R., Nordberg, M. (eds) Metallothionein. Experientia Supplementum, vol 34. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-6493-0_6
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