Abstract
It has been shown that monoamines like serotonin and noradrenaline are preferentially metabolized in man by MAO-A, while benzylamine, phenylethylamine, and phenylethanolamine are specific substrates for MAO-B. Other monoamines are metabolized by both forms, but regional differences exist [1]. In the intestine, MAO-A is the dominant form, while MAO-B is preferentially found in platelets and in the brain, especially in the glial cells [2] (see Chapters 2, 6, 9).
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Wessel, K. (1993). MAO-B Inhibitors in Neurological Disorders with Special Reference to Selegiline. In: Szelenyi, I. (eds) Inhibitors of Monoamine Oxidase B. Milestones in Drug Therapy. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-6348-3_13
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