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Coupling Between Electron Flow and Ion Translocation in the Inner Mitochondrial Membrane

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Biological Aspects of Electrochemistry

Part of the book series: Experientia Supplementum ((EXS,volume 18))

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Summary

Some aspects of the electrochemical nature of various ion translocation reactions across the mitochondrial membrane have been examined, together with a study of the coupling of respiration driven fluxes to oxido-reduction, and of secondary coupling among the ion fluxes. The results show that the respiration driven proton current is of an electrogenic type and a series of translocators, which mediate electrically neutral exchange-diffusion of protons with cations, of hydroxyl ions with Pi and pyruvate, and specific anion-anion exchanges, exist in the mitochondrial membrane. Thus a complex network of cyclic flows is established across the membrane. Through this network the main dissipative flow of the cell (respiration) is directly or indirectly linked to specific group and solute flows.

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Authors and Affiliations

  1. Istituto di Chimica Biologica, Università di Bari, Bari, Italy

    E. Quagliarello & S. Papa

Authors
  1. E. Quagliarello
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  2. S. Papa
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Editor information

Editors and Affiliations

  1. Istituto Superiore di Sanità, Rome, Italy

    Giulio Milazzo

  2. Istituto Chimico dell’Università, Rome, Italy

    Peter E. Jones (Visiting Professor) (Visiting Professor)

  3. Istituto di Chimica, Facoltà di Ingegneria dell’Università, Rome, Italy

    Liliana Rampazzo

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© 1971 Springer Basel AG

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Quagliarello, E., Papa, S. (1971). Coupling Between Electron Flow and Ion Translocation in the Inner Mitochondrial Membrane. In: Milazzo, G., Jones, P.E., Rampazzo, L. (eds) Biological Aspects of Electrochemistry. Experientia Supplementum, vol 18. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5848-9_7

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  • DOI: https://doi.org/10.1007/978-3-0348-5848-9_7

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-5850-2

  • Online ISBN: 978-3-0348-5848-9

  • eBook Packages: Springer Book Archive

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