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Polyamine and Magnesium Effects on Mitochondrial Respiration in Control and Heat-Acclimated Rats

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Effectors of Thermogenesis

Part of the book series: Experientia Supplementum ((EXS,volume 32))

Abstract

Studies were made of polyamine and Mg++ effects on rat liver mitochondrial α ketoglutarate oxidase (αKGO) and succinoxidase (SO). High spermidine levels suppress S3 and S4 of αKGO at 0.6–1.17 mM Mg++: some combinations of it and Mg++ increase the respiratory control ratio (RCR). Spermine suppresses S4 of αKGO and increases the RCR but suppresses the RCR of SO at high levels. In heat-acclimated (HA) animals in which we have studied only spermine effects on αKGO, RCRs of HA rats are greatly increased compared to those of controls.

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References

  1. Bachrach, U.: Function of Naturally Occurring Polyamines. Academic Press, N.Y. 1973.

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  2. Chaffee, R.R.J., Salganicoff, L., Arine, R.M., Rochelle, R.H. and Schultz, E.L.: Polyamine Effects on Succinate-Linked and αKetoglutarate-Linked Rat Liver Mitochondrial Respiration. Biochem. Biophys. Res. Commun. (In Press) (1977).

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  3. Cohen, S.S.: Introduction to the Polyamines. Prentice-Hall, Inc. Englewood Cliff, N.J. 1971.

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  4. Harris, E.J., Catlin, G. and Pressman, B.C.: Effect of Transport-Inducing Antibiotics and Other Agents on Potassium Flux in Mitochondria. Biochemistry 6 (1967) 1360–1369.

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  5. Salganicoff, L.: Effect of Polyamines on Oxidative Phosphorylation and Other Functions in Rat Liver Mitochondria. Fed. Proc. 27 (1968) 527.

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  6. Veloso, D., Guynn, R.W., Oskarsson, M. and Veech, R.L.: The Concentration of Free and Bound Magnesium in Rat Tissues. J. Biol. Chem. 248 (1973) 4811–4819.

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Author information

Authors and Affiliations

  1. Department of Ergonomics, University of California, Santa Barbara, California, 93106, USA

    Rowand R. J. Chaffee, Robert M. Rochelle Arine, H. Rene & Charles D. Walker

Authors
  1. Rowand R. J. Chaffee
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  2. Robert M. Rochelle Arine
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  3. H. Rene
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  4. Charles D. Walker
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Editor information

Editors and Affiliations

  1. Department of Physiology, Medical School, Geneva, Switzerland

    L. Girardier  & J. Seydoux  & 

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© 1978 Springer Basel AG

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Chaffee, R.R.J., Arine, R.M.R., Rene, H., Walker, C.D. (1978). Polyamine and Magnesium Effects on Mitochondrial Respiration in Control and Heat-Acclimated Rats. In: Girardier, L., Seydoux, J. (eds) Effectors of Thermogenesis. Experientia Supplementum, vol 32. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5559-4_10

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  • DOI: https://doi.org/10.1007/978-3-0348-5559-4_10

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-5561-7

  • Online ISBN: 978-3-0348-5559-4

  • eBook Packages: Springer Book Archive

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