Abstract
During exercise of short duration in healthy man, the increase in alveolar ventilation is precisely matched to the increased tissue CO2 production. Hence arterial is closely regulated near resting levels and the only change in pH is secondary to an uncompensated metabolic acidosis.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alexander, S. C., Cohen, P., Wollman, H., Smith, T. C., Reivich, M. and Van Der Molen, R. A.: Cerebral carbohydrate metabolism during hypocarbia in man. Anesthesiology 26, 624–633 (1965).
Betz, E.: Cerebral blood flow: it’s measurement and regulation. Physiol. Rev. 52, 595–629 (1972).
Cerny, F., Dempsey, J. A., Reddan, W. G. and Forster, H. V.: Pulmonary gas exchange in non-native residents of high altitude. J. Clin. Invest. 52, 2993–2999 (1973).
Cunningham, D. J. C. and O’riordan, J. L.: The effect of a rise in the temperature of the body on the respiratory response to CO2 at rest. Quart. J. Exper. Phys. 42, 329–336 (1957).
Dempsey, J. A.: Relative significance of specific pulmonary adaptations to altitude acclimatization. Chest 61, (Supplement) 51–52 (1972).
Dempsey, J. A., Forster, H. V., Birnbaum, M. L., Reddan, W. G., Thoden, J. S., Grover, R. F. and Rankin, J.: Control of exercise hyperpnea under varying duration of moderate hypoxic exposure. Resp. Physiol. 16, 213–231 (1972).
Dempsey, J. A. and Rankin, J.: Physiologic adaptation of gas transport systems to muscular exercise in health and disease. Am. J. Phys. Med. 46, 582–648 (1967).
Dempsey, J. A., Reddan, W. G., Rankin, J., Birnbaum, M. L., Forster, H. V., Thoden, J. S. and Grover, R. F.: Effects of acute through life-long hypoxic exposure on exercise pulmonary gas exchange. Resp. Physiol. 13, 62–88 (1971).
Gilbert, R. and Auchihcloss, J. H.: Cardiac and pulmonary function at the exercise breaking point in cardiac patients. Am. J. Med. Sci. 257, 370–380 (1969).
Mitchell, J. H., Wildenthal, K. and Johnson, R. L.: The effects of acid-base disturbances on cardiovascular and pulmonary function. Kidney International 1, 375–389 (1972).
Nadel, J. A., Gold, W. M. and Burgess, J. H.: Early diagnosis of chronic pulmonary vascular obstruction. Am. J. Med. 44, 16–40 (1968).
Nielsen, M.: Die Regulation der Körpertemperatur bei Muskelarbeit. Skand. Arch. Physiol. 79, 193–205 (1938).
Purves, M. J.: The Physiology of the Cerebral Circulation ( Cambridge University Press, London, 1972 ).
Shappell, S. D., Murray, J. A., Bellingham, A. J., Woodson, R. D., Detter J. C. and Lenfant, C.: Adaptation to exercise: role of hemoglobin affirmity for 02 and 2,3-DPG. J. Appl. Physiol. 30, 827–832 (1971).
Thoden, J. S. Dempsey, J. A., Reddan, W. G., Birnbaum, M. L., Forster, H. V., Grover, R. F. and Rankin, J.: Ventilatory work during steady-state response to exercise. Fed. Proc. 28, 1316–1321 (1969).
Thomson, J., Dempsey, J. A., Reddan, W. G., Shahidi, N.T. and Chosy, L. W.: Oxygen transport and oxyhemoglobin dissociation during prolonged muscular work. J. Appl. Physiol, (in press).
Zobl, E. G., Talmes, F. N., Christensen, R. C. and Baer, L. J.: Effect of exercise on cerebral circulation and metabolism. J. Appl. Physiol. 20, 1289–1293 (1965).
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 1975 Springer Basel AG
About this chapter
Cite this chapter
Dempsey, J.A., Thomson, J.M., Alexander, S.C., Forster, H.V., Chosy, L.W. (1975). Respiratory Influences on Acid-Base Status and Their Effects on O2 Transport during Prolonged Muscular Work. In: Howald, H., Poortmans, J.R. (eds) Metabolic Adaptation to Prolonged Physical Exercise. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5523-5_4
Download citation
DOI: https://doi.org/10.1007/978-3-0348-5523-5_4
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-7643-0725-7
Online ISBN: 978-3-0348-5523-5
eBook Packages: Springer Book Archive