The Identification of Kinetical Parameters in Medical Receptor Analysis

Abstract

Within the last decade, receptor studies in cancer tissue have become an important tool for the selection of an appropriate therapy after tumor surgery (cf. [2, 3] and the references cited therein). Receptors are intracellular proteins which bind to corresponding hormones with extremely high affinity. A lack of or an insufficient amount of receptor protein is characteristic for cell degenerations which typically appear in cancer tissue. Since the degree of degeneration depends on the type of cancer, the quantitative determination of receptor protein supplies an important indication whether or not a hormone therapy is likely to be successful [3].