Skip to main content

Surgical Management of Vocal Fold Scars

  • Chapter
  • First Online:
Textbook of Surgery of Larynx and Trachea
  • 706 Accesses

Abstract

Vocal fold scarring is a pathological entity characterized by reduced pliability of the vocal fold and, occasionally, an incomplete glottic closure during phonation. Various causes of vocal fold scarring are described: vocal fold atrophy, congenital or acquired sulcus vocalis, iatrogenic or postsurgical scarring, direct trauma, or as a result of radiation or chronic irritation on reflux disease. In the interest of simplification, it has been proposed different classifications for this larynx disease. Indeed, functional consequences and therapeutic options will be different according to the type of scarring, and it is therefore crucial to understand the vocal fold healing process, the etiopathogenesis of vocal fold scarring, and its biomechanical consequences. A variety of treatment options have been developed in the last decades, but the current therapeutic possibilities are reduced because of the high complexity of the vocal fold microstructure. In any case, the first step in choosing a therapeutic option is the assessment of the patient’s glottic and vocal situation: the treatment should be then orientated towards the main clinical feature, either glottic gap or rigidity. Because of the unpredictability of a surgical intervention’s results, it is recommended to start always with the less traumatizing procedure.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Monday LA, Cornut G, Bouchayer M, Roch JB. Epidermoid cysts of the vocal cords. Ann Otol Rhinol Laryngol. 1983;92:124–7.

    CAS  PubMed  Google Scholar 

  2. Ford CN, Inagi K, Khidr A, Bless DM, Gilchrist KW. Sulcus vocalis: a rational analytical approach to diagnosis and management. Ann Otol Rhinol Laryngol. 1996;105:189–200.

    CAS  PubMed  Google Scholar 

  3. Remacle M, Eckel HE, Antonelli A, Brasnu D, Chevalier D, Friedrich G, Olofsson J, Rudert HH, Thumfart W, de Vincentiis M, Wustrow TP. Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society. Eur Arch Otorhinolaryngol. 2000;257(4):227–31.

    CAS  PubMed  Google Scholar 

  4. Remacle M, Van Haverbeke C, Eckel H, Bradley P, Chevalier D, Djukic V, De Vicentiis M, Friedrich G, Olofsson J, Peretti G, Quer M, Werner J. Proposal for revision of the European Laryngological Society classification of endoscopic cordectomies. Eur Arch Otorhinolaryngol. 2007;264:499–504. https://doi.org/10.1007/s00405-007-0279-z.

    PubMed  Google Scholar 

  5. Hantzakos A, Dikkers FG, Giovanni A, Benninger MS, Remacle M, Sjögren EV, et al. Vocal fold scars: a common classification proposal by the American Laryngological Association and European Laryngological Society. Eur Arch Otorhinolaryngol. 2019;276(8):2289–92.

    PubMed  Google Scholar 

  6. Friedrich G, Dikkers FG, Arens C, Remacle M, Hess M, Giovanni A, et al. Vocal fold scars: current concepts and future directions. Consensus report of the Phonosurgery Committee of the European Laryngological Society. Eur Arch Otorhinolaryngol. 2013;270(9):2491–507.

    CAS  PubMed  Google Scholar 

  7. Hirano M. Phonosurgery: basic and clinical investigation. Otologia (Fukuoka). 1975;21:239–440.

    Google Scholar 

  8. Gugatschka M, Kojima T, Ohno S, Kanemaru S-i, Hirano S. Recruitment patterns of side population cells during wound healing in rat vocal folds. Laryngoscope. 2011;121(8):1662–7.

    PubMed  Google Scholar 

  9. Arens C, Remacle M. Scarred larynx. In: Remacle M, Eckel H, editors. Surgery of the larynx and trachea. 1st ed. Berlin: Springer; 2010. p. 171–6.

    Google Scholar 

  10. Benninger MS, Alessi D, Archer S, et al. Vocal fold scarring: current concepts and management. Otolaryngol Head Neck Surg. 1996;115:474–82.

    CAS  PubMed  Google Scholar 

  11. Friedrich G. Basic principles for indications in phonosurgery. Laryngorhinootologie. 1995;74:663–5.

    CAS  PubMed  Google Scholar 

  12. Friedrich G, Remacle M, Birchall M, Marie JP, Arens C. Defining phonosurgery: a proposal for classification and nomenclature by the Phonosurgery Committee of the European Laryngological Society (ELS). Eur Arch Otorhinolaryngol. 2007;264:1191–200.

    PubMed  Google Scholar 

  13. Martinez Arias A, Remacle M, Lawson G. Treatment of vocal fold scar by carbon dioxide laser and collagen injection: retrospective study on 12 patients. Eur Arch Otorhinolaryngol. 2010;267:1409–14.

    PubMed  Google Scholar 

  14. Benninger MS. Microdissection or microspot CO2 laser for limited vocal fold benign lesions: a prospective randomized trial. Laryngoscope. 2000;110:1–17.

    CAS  PubMed  Google Scholar 

  15. Remacle M, Arens C, Eldin MB, Campos G, Estomba CC, Dulguerov P, et al. Laser-assisted surgery of the upper aero-digestive tract: a clarification of nomenclature. A consensus statement of the European Laryngological Society. Eur Arch Otorhinolaryngol. 2017;274(10):3723–7.

    PubMed  PubMed Central  Google Scholar 

  16. Bouchayer M, Cornut G. Microsurgical treatment of benign vocal fold lesions: indications, technique, results. Folia Phoniatr (Basel). 1992;44:155–84.

    CAS  PubMed  Google Scholar 

  17. Itoh T, Kawasaki H, Morikawa I, Hirano M. Vocal fold furrows. A 10-year review of 240 patients. Auris Nasus Larynx. 1983;10(Suppl):S17–26.

    PubMed  Google Scholar 

  18. Nakayama M, Ford CN, Brandenburg JH, Bless DM. Sulcus vocalis in laryngeal cancer: a histopathologic study. Laryngoscope. 1994;104:16–24.

    CAS  PubMed  Google Scholar 

  19. Sato K, Hirano M. Electron microscopic investigation of sulcus vocalis. Ann Otol Rhinol Laryngol. 1998;107:56–60.

    CAS  PubMed  Google Scholar 

  20. Giovanni A, Chanteret C, Lagier A. Sulcus vocalis: a review. Eur Arch Otorhinolaryngol. 2007;264:337–44.

    PubMed  Google Scholar 

  21. Sunter AV, Yigit O, Huq GE, Alkan Z, Kocak I, Buyuk Y. Histopathological characteristics of sulcus vocalis. Otolaryngol Head Neck Surg. 2011;145:264–9.

    PubMed  Google Scholar 

  22. Andreadis K, Hoffman K, D’Angelo D, Sulica L. Sulcus vocalis: results of excision without reconstruction. Laryngoscope. 2020;130(9):2208–12.

    PubMed  Google Scholar 

  23. Sataloff RT, Spiegel JR, Heuer RJ, et al. Laryngeal minimicroflap: a new technique and reassessment of the microflap saga. J Voice. 1995;9(2):198–204.

    CAS  PubMed  Google Scholar 

  24. Prufer N, Woo P, Altman KW. Pulse dye and other laser treatments for vocal scar. Curr Opin Otolaryngol Head Neck Surg. 2010;18:492–7.

    PubMed  Google Scholar 

  25. Zeitels SM, Burns JA. Office-based laryngeal laser surgery with the 532-nm pulsed-potassium-titanyl-phosphate laser. Curr Opin Otolaryngol Head Neck Surg. 2007;15:394–400.

    PubMed  Google Scholar 

  26. Mortensen MM, Woo P, Ivey C, Thompson C, Carroll L, Altman K. The use of the pulse dye laser in the treatment of vocal fold scar: a preliminary study. Laryngoscope. 2008;118:1884–8.

    PubMed  Google Scholar 

  27. Carroll LA, Hanasono MM, Mikulec AA, Kita M, Koch RJ. Triamcinolone stimulates bFGF production and inhibits TGF-[beta]1 production by human dermal fibroblasts. Dermatol Surg. 2002;28(8):704–9.

    PubMed  Google Scholar 

  28. Mortensen M, Woo P. Office steroid injections of the larynx. Laryngoscope. 2006;116:1735–9.

    PubMed  Google Scholar 

  29. Young W, Hoffman MR, Koszewski IJ, Whited CW, Ruel BN, Dailey SH. Voice outcomes following a single office-based steroid injection for vocal fold scar. Otolaryngol Head Neck Surg. 2016;155(5):820–8.

    PubMed  Google Scholar 

  30. Hertegard S, Dahlqvist A, Goodyer E. Viscoelastic measurements after vocal fold scarring in rabbits—short-term results after hyaluronan injection. Acta Otolaryngol. 2006;126(7):758–63.

    CAS  PubMed  Google Scholar 

  31. Mattei A, Magalon J, Bertrand B, Philandrianos C, Veran J, Giovanni A. Cell therapy and scarred vocal folds. Eur Ann Otorhinolaryngol Head Neck Dis. 2017;1879–296(17):30103–5.

    Google Scholar 

  32. Graupp M, Bachna-Rotter S, Gerstenberger C, Friedrich G, Fröhlich-Sorger E, Kiesler K, et al. The unsolved chapter of vocal fold scars and how tissue engineering could help us solve the problem. Eur Arch Otorhinolaryngol. 2016;273(9):2279–84.

    CAS  PubMed  Google Scholar 

  33. Gugatschka M, Ohno S, Saxena A, Hirano S. Regenerative medicine of the larynx. Where are we Today? A review. J Voice. 2012;26(5):670.e7–670.e13.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alexia Mattei .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Giovanni, A., Mattei, A. (2022). Surgical Management of Vocal Fold Scars. In: Remacle, M., Eckel, H.E. (eds) Textbook of Surgery of Larynx and Trachea. Springer, Cham. https://doi.org/10.1007/978-3-031-09621-1_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-09621-1_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-09620-4

  • Online ISBN: 978-3-031-09621-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics