Skip to main content

Knowledge Discovery of the Delays Experienced in Reporting COVID-19 Confirmed Positive Cases Using Time to Event Models

  • Conference paper
  • First Online:
Discovery Science (DS 2021)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 12986))

Included in the following conference series:

  • 1480 Accesses

Abstract

Survival analysis techniques model the time to an event where the event of interest traditionally is recovery or death from a disease. The distribution of survival data is generally highly skewed in nature and characteristically can include patients in the study who never experience the event of interest. Such censored patients can be accommodated in survival analysis approaches. During the COVID-19 pandemic, the rapid reporting of positive cases is critical in providing insight to understand the level of infection while also informing policy. In this research, we introduce the very novel application of survival models to the time that suspected COVID-19 patients wait to receive their positive diagnosis. In fact, this paper not only considers the application of survival techniques for the time period from symptom onset to notification of the positive result but also demonstrates the application of survival analysis for multiple time points in the diagnosis pathway. The approach is illustrated using publicly available data for Ontario, Canada for one year of the pandemic beginning in March 2020.

A. Novakovic and A.H. Marshall—Sharing First Authorship

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Naimark, D., et al.: Simulation-based estimation of SARS-CoV-2 infections associated with school closures and community-based nonpharmaceutical interventions in Ontario, Canada. JAMA Netw. Open. 4, 213793 (2021)

    Google Scholar 

  2. Phillips, B., et al.: Model-based projections for COVID-19 outbreak size and student-days lost to closure in Ontario childcare centres and primary schools. Sci. Rep. 11, 6402 (2021)

    Article  Google Scholar 

  3. Vandenberg, O., et al.: Considerations for diagnostic COVID-19 tests. Nat. Rev. Microbiol. 19, 171–183 (2021)

    Article  Google Scholar 

  4. Kerr, C.C., et al.: Controlling COVID-19 via test-trace-quarantine. Nat. Commun. 12, 2993 (2021)

    Article  Google Scholar 

  5. Torres, I., Sippy, R., Sacoto, F.: Assessing critical gaps in COVID-19 testing capacity: the case of delayed results in Ecuador. BMC Pub. Health 21, 1–8 (2021)

    Article  Google Scholar 

  6. Office of the Chief Scientist: National Contact Tracing Review A report for Australia’s National Cabinet (2020)

    Google Scholar 

  7. Ontario Ministry of Health: Confirmed Positive Cases of COVID-19 in Ontario - Datasets - Ontario Data Catalogue. https://bit.ly/3yCiFai

  8. Austin, P.C.: A tutorial on multilevel survival analysis: methods, models and applications. Int. Stat. Rev. 85, 185–203 (2017)

    Article  Google Scholar 

  9. Marshall, A.H., Novakovic, A.: Analysing the performance of a real-time healthcare 4.0 system using shared frailty time to event models. In: 2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS), pp. 622–627 (2019)

    Google Scholar 

  10. Kaplan, E.L., Meier, P.: Nonparametric estimation from incomplete observations. Source J. Am. Stat. Assoc. 53, 457–481 (1958)

    Article  MathSciNet  Google Scholar 

  11. Kartsonaki, C.: Survival analysis. Diagn. Histopathol. 22, 263–270 (2016)

    Article  Google Scholar 

  12. Nemati, M., Ansary, J., Nemati, N.: Machine-Learning Approaches in COVID-19 Survival Analysis and Discharge-Time Likelihood Prediction Using Clinical Data. Patterns 1 (2020)

    Google Scholar 

  13. Marshall, A.H., Zenga, M., Kalamatianou, A.: Academic students’ progress indicators and gender gaps based on survival analysis and data mining frameworks. Soc. Indic. Res. 151(3), 1097–1128 (2020). https://doi.org/10.1007/s11205-020-02416-6

    Article  Google Scholar 

  14. Therneau, T.M., Grambsch, P.M.: Modeling Survival Data: Extending the Cox Model. Springer, New York (2000)

    Book  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Aleksandar Novakovic or Adele H. Marshall .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Novakovic, A., Marshall, A.H., McGregor, C. (2021). Knowledge Discovery of the Delays Experienced in Reporting COVID-19 Confirmed Positive Cases Using Time to Event Models. In: Soares, C., Torgo, L. (eds) Discovery Science. DS 2021. Lecture Notes in Computer Science(), vol 12986. Springer, Cham. https://doi.org/10.1007/978-3-030-88942-5_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-88942-5_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-88941-8

  • Online ISBN: 978-3-030-88942-5

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics