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The Target Locating System for CyberKnife Neuroradiosurgery

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CyberKnife NeuroRadiosurgery
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Abstract

The CyberKnife System uses a combination of in-room X-ray and optical imaging systems, image registration algorithms, and translational and rotational offset corrections applied to the treatment couch robot and treatment delivery robot in order to maintain noninvasive stereotactic alignment during neuroradiosurgery. The sequence of image acquisition—image registration–alignment offset calculation–application of offset corrections, continues throughout every treatment session in order to compensate for intra-treatment motion. Various image registration and offset calculation methods are used depending on the body site being treated, and those methods specific to intracranial and spinal targets are described in this chapter. Finally, phantom-based and clinical methods used to assess the total geometric accuracy of these approaches are described. These methods encompass error contributions from the full end-to-end treatment process of pre-treatment imaging, treatment planning, and treatment delivery. Results of these tests demonstrate that a geometric treatment delivery accuracy <1 mm is consistently achieved during CyberKnife neuroradiosurgery.

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References

  1. Kilby W, Naylor M, Dooley JR, Maurer CR Jr, Sayeh S. A technical overview of the CyberKnife system. In: Abedin-Nasab MH, editor. Handbook of robotic and image-guided surgery. Amsterdam: Elsevier; 2019. p. 15–38.

    Google Scholar 

  2. Fu D, Kuduvalli G. A fast, accurate, and automatic 2D-3D image registration for image-guided cranial radiosurgery. Med Phys. 2008;35:2180–94.

    Article  Google Scholar 

  3. Fu D, Kuduvalli G. Enhancing skeletal features in digitally reconstructed radiographs. Proc SPIE. 2006;6144:846–51.

    Google Scholar 

  4. Fu D, Kuduvalli G, Maurer CR Jr, Allison JW, Adler JR Jr. 3D target localization using 2D local displacements of skeletal structures in orthogonal x-ray images for image-guided spinal radiosurgery. Int J Comput Assist Radiol Surg. 2006;1:198–200.

    Google Scholar 

  5. Fu D, Wang H, Maurer CR Jr, Kuduvalli G. Fiducial-less 2D-3D spine image registration using spine region segmented in CT image. Proc SPIE. 2007;6509:650935.

    Article  Google Scholar 

  6. Sayeh S, Wang J, Main WT, Kilby W, Maurer CR Jr. Respiratory motion tracking for robotic radiosurgery. In: Urschel Jr HC, Kresl JJ, Luketich JD, Papiez L, Timmerman RD, editors. Robotic radiosurgery: treating tumors that move with respiration. Berlin: Springer-Verlag; 2007. p. 15–29.

    Chapter  Google Scholar 

  7. Pantelis E, Petrokokkinos L, Antypas C. Image guidance quality assurance of a G4 CyberKnife robotic stereotactic radiosurgery system. J Instrum. 2009;4:P05009.

    Article  Google Scholar 

  8. Furweger C, Drexler C, Kufeld M, Muacevic A, Wowra B. Advances in fiducial-free image-guidance for spinal radiosurgery with CyberKnife—a phantom study. JACMP. 2011;12:20–8.

    Article  Google Scholar 

  9. Antypas C, Pantelis E. Performance evaluation of a CyberKnife G4 image-guided robotic stereotactic radiosurgery system. Phys Med Biol. 2008;53:4697–718.

    Article  Google Scholar 

  10. Muacevic A, Staehler M, Drexler C, Wowra B, Reiser M, Tonn JC. Technical description, phantom accuracy, and clinical feasibility for fiducial-free frameless real-time image-guided spinal radiosurgery. J Neurosurg Spine. 2006;5:303–12.

    Article  Google Scholar 

  11. Ho AK, Fu D, Cotrutz C, Hancock SL, Chang SD, Gibbs IC, Maurer CR Jr, Adler JR Jr. A study of the accuracy of Cyberknife spinal radiosurgery using skeletal structure tracking. Neurosurgery. 2007;60:147–56.

    Google Scholar 

  12. Kilby W, Dooley JR, Kuduvalli G, Sayeh S, Maurer CR Jr. The CyberKnife® robotic radiosurgery system in 2010. Technol Cancer Res Treat. 2010;9:433–52.

    Article  CAS  Google Scholar 

  13. Pantelis E, Moutsatsos A, Antypas C, Zoros E, Pantelakos P, Lekas L, Romanelli P, Zourari K, Hourdakis CJ. On the total system error of a robotic radiosurgery system: phantom measurements, clinical evaluation and long-term analysis. Phys Med Biol. 2018;63:165015.

    Article  CAS  Google Scholar 

  14. Hoogeman MS, Nuyttens JJ, Levendag PC, Heijmen BJ. Time dependence of intrafraction patient motion assessed by repeat stereoscopic imaging. Int J Radiat Oncol Biol Phys. 2008;70:609–18.

    Article  Google Scholar 

  15. Murphy MJ. Intrafraction geometric uncertainties in frameless image-guided radiosurgery. Int J Radiat Oncol Biol Phys. 2009;73:1364–8.

    Article  Google Scholar 

  16. Fürweger C, Drexler C, Kufeld M, Muacevic A, Wowra B, Schlaefer A. Patient motion and targeting accuracy in robotic spinal radiosurgery: 260 single-fraction fiducial-free cases. Int J Radiat Oncol Biol Phys. 2010;78:937–45.

    Article  Google Scholar 

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Acknowledgments

The author would like to acknowledge his colleagues Kolos Lugosi and Jonathan McCoy in the Accuray Research & Development team for helpful discussions during the preparation of this chapter.

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Correspondence to Warren Kilby .

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Kilby, W. (2020). The Target Locating System for CyberKnife Neuroradiosurgery. In: Conti, A., Romanelli, P., Pantelis, E., Soltys, S., Cho, Y., Lim, M. (eds) CyberKnife NeuroRadiosurgery . Springer, Cham. https://doi.org/10.1007/978-3-030-50668-1_4

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