Abstract
The clinical recognition of solar lentigo (SL), seborrheic keratosis (SK), lichen planus-like keratosis (LPLK), and dermatofibroma (DF) can be very challenging due to the overlapping features they shares with other pigmented and non-pigmented lesions both malignant and benignant.
Noninvasive diagnostic techniques can assist in differential diagnosis.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Cohen LM. Lentigo maligna and lentigo maligna melanoma. J Am Acad Dermatol. 1995;33:923–36; quiz 37–40.
Bugatti L, Filosa G. Dermoscopy of lichen planus-like keratosis: a model of inflammatory regression. J Eur Acad Dermatol Venereol. 2007;21:1392–7.
de Giorgi V, Massi D, Salvini C, Sestini S, Carli P. Features of regression in dermoscopic diagnosis: a confounding factor? Two clinical, dermoscopic-pathologic case studies. Dermatol Surg. 2006;32:282–6.
Langley RG, Burton E, Walsh N, Propperova I, Murray SJ. In vivo confocal scanning laser microscopy of benign lentigines: comparison to conventional histology and in vivo characteristics of lentigo maligna. J Am Acad Dermatol. 2006;55:88–97.
Rajadhyaksha M, Grossman M, Esterowitz D, Webb RH, Anderson RR. In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast. J Invest Dermatol. 1995;104:946–52.
Propperova I, Langley RG. Reflectance-mode confocal microscopy for the diagnosis of sebaceous hyperplasia in vivo. Arch Dermatol. 2007;143(1):134.
Fraga-Braghiroli NA, Stephens A, Grossman D, Rabinovitz H, Castro RP, Scope A. Use of handheld reflectance confocal microscopy for in vivo diagnosis of solitary facial papules: a case series. J Eur Acad Dermatol Venereol. 2014;28(7):933–42.
Elgart GW. Seborrheic keratoses, solar lentigines, and lichenoid keratoses. Dermatoscopic features and correlation to histology and clinical signs. Dermatol Clin. 2001;19(2):347–57.
González S, Gill M, Halpern AC. Reflectance confocal microscopy of cutaneous tumors. An atlas with clinical, dermoscopic and histological correlations. London: Informa healthcare; 2008.
Langley RGB, Burton E, Walsh N, et al. In vivo confocal scanning laser microscopy of benign lentigines: comparison to conventional histology and in vivo characteristics of lentigo maligna. J Am Acad Dermatol. 2006;55:88–97.
de Carvalho N, Farnetani F, Ciardo S, Ruini C, Witkowski AM, Longo C, Argenziano G, Pellacani G. Reflectance confocal microscopy correlates of dermoscopic patterns of facial lesions help to discriminate lentigo maligna from pigmented nonmelanocytic macules. Br J Dermatol. 2015 Jul;173(1):128–33.
Braun RP, Rabinovitz HS, Krischer J. Dermoscopy of pigmented seborrheic keratosis: a morphological study. Arch Dermatol. 2002;138(12):1556–60.
Kopf AW, Rabinovitz H, Marghoob A, Braun RP, Wang S, Oliviero M, Polsky D. “Fat fingers”: a clue in the dermoscopic diagnosis of seborrheic keratoses. J Am Acad Dermatol. 2006;55(6):1089–91.
Ahlgrimm-Siess V, Cao T, Oliviero M, et al. Seborrheic keratosis: reflectance confocal microscopy features and correlation with dermoscopy. J Am Acad Dermatol. 2013;69(1):120–6.
Longo C, Zalaudek I, Moscarella E, et al. Clonal seborrheic keratosis: Dermoscopic and confocal microscopy characterization. J Eur Acad Dermatol Venereol. 2014;28(10):1397–400.
Busam KJ, Charles C, Lee G, Halpern AC. Morphologic fea- tures of melanocytes, pigmented keratinocytes and melano- phages by in vivo confocal scanning laser microscopy. Mod Pathol. 2001;14(9):862–8.
Pezzini C, Mandel VD, Persechino F, Ciardo S, Kaleci S, Chester J, De Carvalho N, Persechino S, Pellacani G, Farnetani F. Seborrheic keratoses mimicking melanoma unveiled by in vivo reflectance confocal microscope. Skin Res Technol. 2018 May;24(2):285–93.
Laur WE, Posey RE, Waller JD. Lichen planus-like keratosis. A clinic histopathologic correlation. A clinicohistopathologic correlation. J Am Acad Dermatol. 1981;4(3):329–33.
Bassoli S, Rabinovitz HS, Pellacani G, et al. Reflectance confocal microscopy criteria of lichen planus-like keratosis. J Eur Acad Dermatol Venereol. 2012;26:578–90.
Sánchez V, González S. Dermatofibroma. In: González S, editor. Reflectance confocal microscopy in dermatology: fundamentals and clinical applications. Madrid: Grupo aula médica; 2012. p. 113–4.
Moscarella E, Zalaudek I, Ferrara G, Catricalà C, Argenziano G. Potpourri of nonmelanocytic skin lesions. In: Hofmann-Wellenhoff R, Pellacani G, Malvehy J, Soyer HP, editors. Reflectance confocal microscopy for skin diseases. Berlin: Springer; 2012. p. 336–8.
Scope A, Ardigo M, Marghoob AA. Correlation of dermoscopic globule-like structures of dermatofibroma using reflectance confocal microscopy. Dermatology. 2008;216:81–2.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Farnetani, F., Ciardo, S., Pellacani, G. (2020). In Vivo Reflectance Confocal Microscopy for Nonmelanocytic Benign Skin Tumors. In: Fimiani, M., Rubegni, P., Cinotti, E. (eds) Technology in Practical Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-45351-0_15
Download citation
DOI: https://doi.org/10.1007/978-3-030-45351-0_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-45350-3
Online ISBN: 978-3-030-45351-0
eBook Packages: MedicineMedicine (R0)