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Porous Scaffolds of Polyvinyl Pyrrolidone/Polyethylene Glycol/Nano-Diamond Using Gamma Irradiation

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Eco-friendly and Smart Polymer Systems (ISPST 2018)

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Abstract

Blends of polyvinyl pyrrolidone/polyethylene glycol (PVP/PEG) along with 1–3% nano-diamond particles (ND) were irradiated by gamma ray at various doses and then subjected to freeze-drying method to render porous scaffolds. At 35 kGy irradiation dose, the gel content was higher than 90%, though the presence of nanoparticles reduced slightly the gel content. It was found that for 10 kGy increase in irradiation dose, there was 15% reduction in pore size. On the other hand, upon the addition of 1% nano-diamond to PVP/PEG blends, the water swelling content of the scaffolds was increased by 10%. Also, the SEM images showed, at 1% nano-diamond level, the pore size was larger than pore size of neat PVP/PEG blends. The scaffolds were also tested for bio-compatibility, bio-degradability and mechanical properties. The results verified the suitability of these scaffolds for bio-medical applications.

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Correspondence to Masoud Frounchi .

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Jabbar, A., Dadbin, S., Frounchi, M. (2020). Porous Scaffolds of Polyvinyl Pyrrolidone/Polyethylene Glycol/Nano-Diamond Using Gamma Irradiation. In: Mirzadeh, H., Katbab, A. (eds) Eco-friendly and Smart Polymer Systems. ISPST 2018. Springer, Cham. https://doi.org/10.1007/978-3-030-45085-4_2

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