Abstract
The aim of this study was to build a modern system with controlled release to improve the wound healing because sometimes the body alone is not capable of repair and wound closure. Due to evidence for beneficial effects of nitric oxide at any stage of wound healing (for example, induction of inflammation, angiogenesis, cell proliferation, matrix deposition, and reconstruction), treatments based on nitric oxide has been proved to be suitable for wound healing. Different amounts of sodium nitrite (2 and 4 wt%) were added to silk fibroin solution and its effect on the morphology, release profile and fibroblast viability fibers were investigated and compared to those of pure silk fibroin.
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References
Kim, J.O., et al.: Int. J. Biol. Macromol. 79, 217–225 (2015)
Kasoju, N., Bora, U.: Adv. Healthc. Mater. 1(4), 393–412 (2012)
Lowe, A., Bills, J., Verma, R., Lavery, L., Davis, K., Balkus Jr., K.J.: Acta Biomater. 13, 121–130 (2015)
Li, C.Q., Pang, B., Kiziltepe, T., Trudel, L.J.: Chem. Res. Toxicol. 19(3), 399–406 (2006)
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Ghasemi, M.V., Nourmohammadi, J. (2020). Fabrication of NO-Releasing Silk Fibroin Nanofiber for Wound Dressing Application. In: Mirzadeh, H., Katbab, A. (eds) Eco-friendly and Smart Polymer Systems. ISPST 2018. Springer, Cham. https://doi.org/10.1007/978-3-030-45085-4_19
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DOI: https://doi.org/10.1007/978-3-030-45085-4_19
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