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Research on the Pathophysiology of Chiari I-Related Symptoms and Syringomyelia, with Emphasis on Dynamic MRI Techniques

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The Chiari Malformations

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Abstract

The pathophysiology of Chiari-related symptoms and syringomyelia remains enigmatic. Present-day technology, most notably magnetic resonance imaging, is providing progressively more sophisticated opportunities to test traditional as well as contemporary theories while adding to conventional animal models a selection of promising mechanical and computational representations of syringomyelia and its etiologies. We will briefly touch on the past and present of Chiari-related syringomyelia research with emphasis on essential questions related to the development of anatomical anomalies and the constellation of symptoms with which they are associated.

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Author information

Authors and Affiliations

  1. Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, Madison, WI, USA

    Joyce Koueik

  2. Department of Biological Engineering, University of Idaho, Neurophysiological Imaging and Modeling Laboratory, Moscow, ID, USA

    Bryn A. Martin

  3. Department of Neurological Surgery, Pediatric Neurosurgery, University of Wisconsin, Madison, WI, USA

    Bermans J. Iskandar

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  1. Joyce Koueik
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  2. Bryn A. Martin
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  3. Bermans J. Iskandar
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Correspondence to Bermans J. Iskandar .

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Editors and Affiliations

  1. Department of Neurosurgery, Tulane University School of Medicine, New Orleans, LA, USA

    R. Shane Tubbs

  2. Department of Neurosurgery, Aydın Adnan Menderes University School of Medicine, Efeler, Aydın, Turkey

    Mehmet Turgut

  3. Departments of Neurosurgery and Pediatrics, University of Alabama, Birmingham, AL, USA

    W. Jerry Oakes

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Koueik, J., Martin, B.A., Iskandar, B.J. (2020). Research on the Pathophysiology of Chiari I-Related Symptoms and Syringomyelia, with Emphasis on Dynamic MRI Techniques. In: Tubbs, R., Turgut, M., Oakes, W. (eds) The Chiari Malformations. Springer, Cham. https://doi.org/10.1007/978-3-030-44862-2_12

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