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Toxic Acute Kidney Injury

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Tropical Nephrology

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Abstract

Exposure to a wide range of toxic agents that induce nephrotoxicity is a public health problem, specifically in developing countries. The interactions and mechanisms between these substances and the body could produce relevant disorders such as toxic acute kidney injury (AKI). Ingestion or inhalation of nephrotoxic substances is the primary way of community-acquired AKI. Poisoning by plants, animals, medications, chemicals, and illicit drugs induces AKI and has different mechanisms of nephrotoxicity. The recognition of toxic mechanisms in different acute poisonings and envenomation is crucial to plan effective treatment. In this chapter, we focus on the most relevant causes of toxic-AKI due to drugs, self-poisoning with pesticides, toxic plants, chemicals such as laundry detergents, herbal medicines, and snakebite envenomation, and the use of extracorporeal therapies for some toxic agents.

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Authors and Affiliations

  1. Center for Toxicological Assistance and Information, Instituto Dr. Jose Frota, Fortaleza, Ceara, Brazil

    Polianna Lemos Moura Moreira Albuquerque

  2. School of Medicine, University of Fortaleza, Fortaleza, Ceara, Brazil

    Polianna Lemos Moura Moreira Albuquerque

  3. Translational Australian Clinical Toxicology Program, The University of Sydney, Sydney, NSW, Australia

    Fathima Shihana

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  1. Polianna Lemos Moura Moreira Albuquerque
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Editors and Affiliations

  1. University of Fortaleza, Fortaleza, Ceará, Brazil

    Geraldo Bezerra da Silva Junior

  2. Federal University of Ceará, Fortaleza, Ceará, Brazil

    Elizabeth De Francesco Daher

  3. Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

    Elvino Barros

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Albuquerque, P.L.M.M., Shihana, F. (2020). Toxic Acute Kidney Injury. In: Bezerra da Silva Junior, G., De Francesco Daher, E., Barros, E. (eds) Tropical Nephrology. Springer, Cham. https://doi.org/10.1007/978-3-030-44500-3_5

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