Homing of Stem Cells to the Bone Marrow: Finding the Way Home
- 105 Downloads
Once stem cells are introduced in the patient’s blood, they proceed with a systematic migration to their bone marrow, through a process called homing. Since “homing instinct,” according to the Merriam-Webster’s dictionary, is an ability to return home from a great distance, which is related with an animal with a homing instinct, homing is a very didactic word to also call the process through stem cells find their way home starting from the blood. Although stem cells need to achieve the patient’s bone marrow, they are infused through the patient’s vein, like transfusions, because of the homing process—in which stem cells will find the bone marrow.
- 8.Kurzrock R. Stem cell factor. In: Kufe DW, Pollock RE, Weichselbaum RR, et al., editors. Holland-frei cancer medicine. 6th ed. Hamilton: BC Decker; 2003.Google Scholar
- 12.O’Shea JJ, Gadina M, Siegel RM. Cytokines and cytokine receptors. In: Clinical immunology: principles and practice. 5th ed. Philadelphia: Elsevier; 2019. p. 127–55. el.Google Scholar
- 17.Alberts B, Johnson A, Lewis J, et al. Molecular biology of the cell. 4th ed. New York: Garland Science; 2002.Google Scholar
- 20.Mouse Genome Informatics. Inbred strains of mice: CBA. http://www.informatics.jax.org/inbred_strains/mouse/docs/CBA.shtml (June 17, 2019).