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The Pharmacist in Pediatric Hematopoietic Stem Cell Transplantation

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Abstract

Hematopoietic stem cell transplantation (HSCT) has been used for a variety of malignant and nonmalignant diseases of the blood and immune-system in adults, children, and even infants. The HSCT involves the ablation of the bone marrow of the recipient with high doses of chemotherapy, and in some cases also radiation, to allow engraftment of the donor cells. It is autologous when the cells are from the own patient and allogeneic when the cells comes from a donor. The ability to successfully transplant hematopoietic stem cells to reconstitute the hematopoietic system is a relatively new area and in constant development [34, 91].

References

  1. 34.
    Dessels C, Alessandrini M, Pepper MS. Factors influencing the umbilical cord blood stem cell industry: an evolving treatment landscape. Stem Cells Transl Med. 2018;7(9):643–50. https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/sctm.17-0244 (Aug 13, 2019).CrossRefGoogle Scholar
  2. 91.
    Hastings CA, Torkildson JC, Agrawal AK. Handbook of pediatric hematology and oncology: children’s Hospital & Research Center Oakland. 2nd ed. New York: Wiley Blackwell; 2013.Google Scholar

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.CuritibaBrazil

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