The Pharmacist in Pediatric Hematopoietic Stem Cell Transplantation
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Hematopoietic stem cell transplantation (HSCT) has been used for a variety of malignant and nonmalignant diseases of the blood and immune-system in adults, children, and even infants. The HSCT involves the ablation of the bone marrow of the recipient with high doses of chemotherapy, and in some cases also radiation, to allow engraftment of the donor cells. It is autologous when the cells are from the own patient and allogeneic when the cells comes from a donor. The ability to successfully transplant hematopoietic stem cells to reconstitute the hematopoietic system is a relatively new area and in constant development [34, 91].
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