Abstract
We investigate the hemodynamic impacts of flow diverters in intracranial aneurysms using computer simulations. The geometry of the aneurysm is reconstructed using the open-source software Slicer3D to create a three-dimensional model of the aneurysm. In addition, the geometries of the flow diverters is reconstructed in a mesh-like structure using the commercial software Gridgen and Meshmixer. First, using the provided the blood flow condition at the Internal Carotid Artery as the boundary condition, our in-house code (Virtual Flow Simulator) is applied to simulate the flow dynamics within the aneurysms without flow diverter implantation. The spatial and temporal distribution of wall shear stress (WSS) are computed from the simulation results over the aneurysm dome. At the second step, the virtual implantation of the flow diverter is carried out at the ostium. A second simulation with the implanted flow diverter is carried out to provide hemodynamic conditions after the implantation. Our results show a stark contrast on flow distribution between two cases. The flow diverter not only changes the flow distribution at the ostium level but it also alters the flow distribution across the parent artery. Our results indicate that the flow pulsatility plays a key role in mediating the interaction between the incoming jet and the weave pores. Our simulations suggest that the weave’s size correlates well to the small-scale structures of the instantaneous flow in the vicinity of the ostium.
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Acknowlegement
This project is partially supported by NSF ND EPSCOR project FAR0030612. We thank graduate student Venkata Kanumuru for preparing the three-dimensional model of the aneurysm. This work is supported by the start-up package of Trung Bao Le from the Department of Civil and Environmental Engineering, North Dakota State University. The computational work has been performed using the computational resources of Center for Computationally Assisted Science and Technology (CCAST) at North Dakota State University.
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Le, T.B., Eidenschink, E., Drofa, A. (2020). Impacts of Flow Diverters on Hemodynamics of Intracranial Aneurysms. In: Ateshian, G., Myers, K., Tavares, J. (eds) Computer Methods, Imaging and Visualization in Biomechanics and Biomedical Engineering. CMBBE 2019. Lecture Notes in Computational Vision and Biomechanics, vol 36. Springer, Cham. https://doi.org/10.1007/978-3-030-43195-2_2
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