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Micronutrients that Affect Immunosenescence

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Reviews on New Drug Targets in Age-Related Disorders

Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1260))

Abstract

The immune system undergoes some adverse changes throughout aging, many of which have been implicated in the increased morbidity and mortality related to infection in the elderly. In addition to intrinsic alterations in the immune system with aging, the elderly are more likely to have poor nutritional status, which further affects the already impaired immune function. Micronutrient deficiencies are a recognized global public health problem, and poor nutritional status predisposes to certain infections. Immune function may be ameliorated by restoring deficient micronutrients to recommended levels, thereby increasing resistance to infection and supporting faster recovery when infected. This review looks at the effects of micronutrient supplementation on immune function during aging.

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Authors and Affiliations

  1. Department of Nutrition, Faculty of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Behnaz Abiri

  2. Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran

    Mohammadreza Vafa

  3. Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran

    Mohammadreza Vafa

Authors
  1. Behnaz Abiri
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  2. Mohammadreza Vafa
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Correspondence to Mohammadreza Vafa .

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Editors and Affiliations

  1. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil

    Paul C. Guest

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Abiri, B., Vafa, M. (2020). Micronutrients that Affect Immunosenescence. In: Guest, P. (eds) Reviews on New Drug Targets in Age-Related Disorders. Advances in Experimental Medicine and Biology(), vol 1260. Springer, Cham. https://doi.org/10.1007/978-3-030-42667-5_2

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