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International Conference on Applied Technologies

ICAT 2019: Applied Technologies pp 108–118Cite as

Comparison of Attenuation Coefficient Estimation in High Intensity Focused Ultrasound Therapy for Cancer Treatment by Levenberg Marquardt and Gauss-Newton Methods

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Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1194))

Abstract

Hyperthermia using High-Intensity Focused Ultrasound (HIFU) is an acoustic therapy used in clinical applications to destroy malignant tumors of bone, breast, brain, kidney, pancreas, prostate, rectum and testicle. This technique consists in increase the temperature in the tumor or the specific area, to achieve coagulative necrosis and immediate cell death. Although hyperthermia can cure cancer, it can also cause side effects and even damage healthy cells or tissues. Therefore, for having a successful treatment, it is important to monitor and observe what is the tissue behavior, as well as its changes, before, during and after the procedure. Mathematical models are tools that can be useful to simulate an adequate therapy by differentiating characteristics that will depend on each individual. An attenuation coefficient estimation for a forward model with a rectangular two-dimensional domain is presented, the estimation was made with simulated numerical data and simulated experimental data by Levenberg Marquardt and Gauss-Newton Methods. The results demonstrate that by identifying the attenuation coefficient of each patient. By estimating the attenuation coefficient parameter it is possible to predict the thermal responses of the tissue to be treated and, based on them, to plan an adequate cancer treatment by inducing heat by HIFU.

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Acknowledgments

The authors are thankful for the support provided by CNPq, CAPES, FAPERJ (Brazil) and DGI of Universidad Santiago de Cali, Colombia, project No. 819- 621118-120.

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Authors and Affiliations

  1. Department of Engineering, Universidad Santiago de Cali, Street 5 no. 62-00, Cali, Colombia

    Laura de los Ríos Cárdenas & Leonardo A. Bermeo Varón

  2. Department of Biomedical Engineering, Universidade Federal de Rio de Janeiro, Av. Horácio Macedo 2030, Centro de Tecnologia, COPPE/UFRJ, Rio de Janeiro, Brazil

    Wagner Coelho de Albuquerque Pereira

Authors
  1. Laura de los Ríos Cárdenas
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  2. Leonardo A. Bermeo Varón
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  3. Wagner Coelho de Albuquerque Pereira
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Corresponding author

Correspondence to Leonardo A. Bermeo Varón .

Editor information

Editors and Affiliations

  1. Eindhoven University of Technology, Eindhoven, The Netherlands

    Miguel Botto-Tobar

  2. Universidad Técnica del Norte, Ibarra, Ecuador

    Marcelo Zambrano Vizuete

  3. Universidad Técnica Particular de Loja, Loja, Ecuador

    Pablo Torres-Carrión

  4. Universidad de las Fuerzas Armadas (ESPE), Quito, Ecuador

    Sergio Montes León

  5. Universidad Politécnica Salesiana, Guayaquil, Ecuador

    Guillermo Pizarro Vásquez

  6. International University of Sarajevo, Sarajevo, Bosnia and Herzegovina

    Benjamin Durakovic

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de los Ríos Cárdenas, L., Bermeo Varón, L.A., Pereira, W.C.d.A. (2020). Comparison of Attenuation Coefficient Estimation in High Intensity Focused Ultrasound Therapy for Cancer Treatment by Levenberg Marquardt and Gauss-Newton Methods. In: Botto-Tobar, M., Zambrano Vizuete, M., Torres-Carrión, P., Montes León, S., Pizarro Vásquez, G., Durakovic, B. (eds) Applied Technologies. ICAT 2019. Communications in Computer and Information Science, vol 1194. Springer, Cham. https://doi.org/10.1007/978-3-030-42520-3_9

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  • DOI: https://doi.org/10.1007/978-3-030-42520-3_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-42519-7

  • Online ISBN: 978-3-030-42520-3

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