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Nanoparticle-Based Antimicrobial Coating on Medical Implants

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Nanostructures for Antimicrobial and Antibiofilm Applications

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

Abstract

Infections after implantation are the major concern in the field of clinical surgery. The microbial adhesion on the surface of implant favors for colonization and biofilm formation. The host immune system and systemic antibiotics could have not inhibited the microbial adhesion and growth, which resulted in sepsis. Thus, surface modification of implants has gained attention to prevent the bacterial adhesion on the surface of the implant. Various coating methods have been developed, namely, passive surface coating, active surface coating, and local carriers or coatings, with the aim of preventing microbial adhesion and biofilm formation. Nanoparticle coating is one potential alternative for successful clinical outcomes. This book chapter aims to give a brief report on the need of coating on the implants against the bacterial colonization on the surface of the implant and especially the role of nanoparticle-based antimicrobial coated medical devices in the prevention of sepsis.

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Authors and Affiliations

  1. Brien Holden Eye Research Centre, L V Prasad Eye Institute, Banjara Hills, Hyderabad, India

    Birru Bhaskar

  2. Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Jonjyoti Kalita, Papori Buragohain & Utpal Bora

  3. Center for the Environment, Indian Institute of Technology Guwahati, Guwahati, Assam, India

    Jintu Dutta & Ponnala Vimal Mosahari

  4. Department of Chemical Engineering, National Institute of Technology Warangal, Warangal, Telangana, India

    Shalini

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  1. Birru Bhaskar
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  2. Jintu Dutta
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  3. Shalini
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Editors and Affiliations

  1. Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India

    Ram Prasad

  2. Department of Microbiology, School of Life Sciences, Pondicherry University, Pondicherry, India

    Busi Siddhardha

  3. Department of Biochemistry & Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India

    Madhu Dyavaiah

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Bhaskar, B. et al. (2020). Nanoparticle-Based Antimicrobial Coating on Medical Implants. In: Prasad, R., Siddhardha, B., Dyavaiah, M. (eds) Nanostructures for Antimicrobial and Antibiofilm Applications. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-40337-9_4

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