Abstract
The yellow pigments have a marked alleviative effect on some major sight disturbances. Their concentration in the whole-bread is much higher than in the white bread. This phenomenon as it justified the consumption of the whole-bread. In particular, the whole-wheat bread is crucial for the aging population with a high prevalence of sight disturbances. According to the market demand, through generations, bread wheat cultivars have selected to produce a white “clean” flour with a lower content of the yellow pigments. High time has approached to restore and increase the content of these marvelous compounds to our menu.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Abdel-Aal ESM, Young JC, Wood PJ, Rabalski I, Hucl P, Falk D, Frégeau-Reid J (2002) Einkorn: a potential candidate for developing high lutein wheat. Cereal Chem 79:455–457. https://doi.org/10.1094/CCHEM.2002.79.3.455
Abdel-Aal ESM, Akhtar H, Zaheer K, Ali R (2013) Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health. Nutrients 5:1169–1185. https://doi.org/10.3390/nu5041169
Ajana S, Weber D, Helmer C, Merle BM, Stuetz W, Dartigues J-F, Rougier M-B, Korobelnik J-F, Grune T, Delcourt C, Feart C (2018) Plasma concentrations of lutein and zeaxanthin, macular pigment optical density, and their associations with cognitive performances among older adults. Invest Ophthalmol Vis Sci 59:1828–1835. https://doi.org/10.1167/iovs.17-22656
Anderson DF, Dhariwal M, Bouchet C, Keith MS (2018) Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review. Clin Ophthalmol 12:439–452. https://www.dovepress.com/terms.php
Arunkumar R, Calvo CM, Conrady CD, Bernstein PS (2018) What do we know about the macular pigment in AMD: the past, the present, and the future. Eye 32:992–1004. https://doi.org/10.1038/s41433-018-0044-0
Carneiro Â, Andrade JP (2017) Nutritional and lifestyle interventions for age-related macular degeneration: a review. Oxidative Med Cell Longev 2017:6469138–6469113. https://doi.org/10.1155/2017/6469138
Brown L, Rimm EB, Seddon JM, Giovannucci EL, Chasan-Taber L, Spiegelman D, Willett WC, Hankinson SE (1999) A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 70:517–524
Clarke FR, Clarke JM, McCaig TN, Knox RE, DePauw RM (2011) Inheritance of yellow pigment concentration in seven durum wheat crosses. Can J Plant Sci 86:133–141. https://doi.org/10.4141/p05-083
Crews JE, Chou CF, Sekar S, Saaddine JB (2017) The prevalence of chronic conditions and poor health among people with and without vision impairment, aged ≥65 years, 2010–2014. Am J Ophthalmol 182:18–30. https://doi.org/10.1016/j.ajo.2017.06.038
Cui YH, Jing CX, Pan HW (2013) Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies. Am J Clin Nutr 98:778–786. https://doi.org/10.3945/ajcn.112.053835
Delcourt C, Carrière I, Delage M, Barberger-Gateau P, Schalch W, Lacroux A, Fourrey S, Covacho MJ, Canet C, Paillard P, Ponton-Sanchez A, Defay R, Colvez A, Papoz L, Balme-Blanchard C, Balmelle L, Chinaud D, Costeau J, Diaz JL, Dossa C, Gallinaro C, Malan P, Robert F, Arnaud B, Cristol JP, Vernet MH, Fouret G, Michel F, Leger C, Descomps B, Mathieu-Daudé P, Mathieu-Daudé JC, Tessier F, Birlouez-Aragon I (2006) Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA study. Investig Ophthalmol Vis Sci 47:2329–2335. https://doi.org/10.1167/iovs.05-1235
Dror Y, Giveon SM, Stern F (2018) Chap 11: The nadir range of the U-shaped curve. In: series Rattan SIS (Ed) Healthy ageing and longevity vol 8: Malavolta M, Mocchegiani E (Eds) Trace elements and minerals in health and longevity, Springer. pp 303–325. https://doi.org/10.1007/978-3-030-03742-0/
Eggersdorfer M, Wyss A (2018) Carotenoids in human nutrition and health. Arch Biochem Biophys 652:18–26. https://doi.org/10.1016/j.abb.2018.06.001
Eisenhauer B, Natoli S, Liew G, Flood VM (2017) Lutein and zeaxanthin — food sources, bioavailability and dietary variety in age-related macular degeneration protection. Nutrients 9:120. https://doi.org/10.3390/nu9020120
Feart C, Letenneur L, Helmer C, Samieri C, Schalch W, Etheve S, Delcourt C, Dartigues JF, Barberger-Gateau P (2016) Plasma carotenoids are inversely associated with dementia risk in an elderly French cohort. J Gerontol A Biol Sci Med Sci 71:683–688. https://doi.org/10.1093/gerona/glv135
Fu B, Chiremba C, Pozniak C, Wang K, Nam S (2017) Total phenolic and yellow pigment contents and antioxidant activities of durum wheat milling fractions. Antioxidants 6:78. https://doi.org/10.3390/antiox6040078
Giordano E, Quadro L (2018) Lutein, zeaxanthin and mammalian development: metabolism, functions and implications for health. Arch Biochem Biophys 647:33–40. https://doi.org/10.1016/j.abb.2018.04.008
Glaser TS, Doss LE, Shih G, Nigam D, Sperduto RD, Ferris FL, Agrón E, Clemons TE, Chew EY (2015) The association of dietary lutein plus zeaxanthin and B vitamins with cataracts in the age-related eye disease study AREDS report no. 37. Ophthalmology 122:1471–1479. https://doi.org/10.1016/j.ophtha.2015.04.007
Gong X, Draper C, Allison G, Marisiddaiah R, Rubin L (2017) Effects of the macular carotenoid lutein in human retinal pigment epithelial cells. Antioxidants 6:100. https://doi.org/10.3390/antiox6040100
Graham RD, Rosser JM (2000) Carotenoids in staple foods: their potential to improve human nutrition. Food Nutr Bull 21:404–409
Jia YP, Sun L, Yu HS, Liang LP, Li W, Ding H, Song XB, Zhang LJ (2017) The pharmacological effects of lutein and zeaxanthin on visual disorders and cognition diseases. Molecules 22:610. https://doi.org/10.3390/molecules22040610
Johnson EJ (2012) A possible role for lutein and zeaxanthin in cognitive function in the elderly. Am J Clin Nutr 96:1161s–1165s. https://doi.org/10.3945/ajcn.112.034611.1
Johnson EJ (2014) Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan. Nutr Rev 72:605–612. https://doi.org/10.1111/nure.12133
Koller D, Bynum JPW (2015) Dementia in the USA: state variation in prevalence. J Public Heal (United Kingdom) 37:597–604. https://doi.org/10.1093/pubmed/fdu080
Krinsky NI, Landrum JT, Bone RA (2003) Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu Rev Nutr 23:171–201. https://doi.org/10.1146/annurev.nutr.23.011702.073307
Leenhardt F, Lyan B, Rock E, Boussard A, Potus J, Chanliaud E, Remesy C (2006) Genetic variability of carotenoid concentration, and lipoxygenase and peroxidase activities among cultivated wheat species and bread wheat varieties. Eur J Agron 25:170–176. https://doi.org/10.1016/j.eja.2006.04.010
Lindbergh CA, Renzi-Hammond LM, Hammond BR, Terry DP, Mewborn CM, Puente AN, Miller LS (2018) Lutein and zeaxanthin influence brain function in older adults: a randomized controlled trial. J Int Neuropsychol Soc 24:1–14. https://doi.org/10.1017/S1355617717000534
Liu XH, Yu RB, Liu R, Hao ZX, Han CC, Zhu ZH, Ma L (2014) Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. Nutrients 6:452–465. https://doi.org/10.3390/nu6010452
Ma L, Dou HL, Wu YQ, Huang YM, Huang YB, Xu XR, Zou ZY, Lin XM (2012) Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis. Br J Nutr 107:350–359. https://doi.org/10.1017/S0007114511004260
Manikandan R, Thiagarajan R, Goutham G, Arumugam M, Beulaja M, Rastrelli L, Skalicka-Woźniak K, Habtemariam S, Orhan IE, Nabavi SF, Nabavi SM (2016) Zeaxanthin and ocular health, from bench to bedside. Fitoterapia 109:58–66. https://doi.org/10.1016/j.fitote.2015.12.009
Mares J (2016) Lutein and zeaxanthin isomers in eye health and disease. Annu Rev Nutr 36:571–602. https://doi.org/10.1146/annurev-nutr-071715-051110
Mellado-Ortega E, Hornero-Méndez D (2015) Carotenoids in cereals: an ancient resource with present and future applications. Phytochem Rev 14:873–890. https://doi.org/10.1007/s11101-015-9423-3
Moeller SM, Voland R, Tinker L, Blodi BA, Klein ML, Gehrs KM, Johnson MJ, Snodderly DM, Wallace RB, Chappell RJ, Parekh N, Ritenbaugh C, Mares JA (2008) Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the carotenoids in the age-related eye disease study (CAREDS), an ancillary study of the Women’s Health Initiative. Arch Ophthalmol 126:354–364
NIH-US National Eye Institute - Age-Related Eye Diseases in America, Prevalence of adult vision impairment and age-related eye diseases in America, estimated number of cases by vision problem age ≥ 40. https://nei.nih.gov/eyedata/adultvision_usa
NIH-US National Eye Institute - Cataracts Defined Tables, https://nei.nih.gov/eyedata/cataract/tables
Olmedilla B, Granado F, Blanco I, Vaquero M, Cajigal C (2001) Lutein in patients with cataracts and age-related macular degeneration: a long-term supplementation study. J Sci Food Agric 81:904–909. https://doi.org/10.1002/jsfa.905
Ravel C, Dardevet M, Leenhardt F, Bordes J, Joseph JL, Perretant MR, Exbrayat F, Poncet C, Balfourier F, Chanliaud E, Charmet G (2013) Improving the yellow pigment content of bread wheat flour by selecting the three homoeologous copies of Psy1. Mol Breed 31:87–99. https://doi.org/10.1007/s11032-012-9772-1
Rodriguez-Concepcion M, Avalos J, Bonet ML, Boronat A, Gomez-Gomez L, Hornero-Mendez D, Limon MC, Meléndez-Martínez AJ, Olmedilla-Alonso B, Palou A, Ribot J, Rodrigo MJ, Zacarias L, Zhu C (2018) A global perspective on carotenoids: metabolism, biotechnology, and benefits for nutrition and health. Prog Lipid Res 70:62–93. https://doi.org/10.1016/j.plipres.2018.04.004
Schulthess A, Schwember AR (2013) Improving durum wheat (Triticum turgidum L. var durum) grain yellow pigment content through plant breeding. Cienc Investig Agrar 40:475–490
Shewry PR, Hey S (2015) Do “ancient” wheat species differ from modern bread wheat in their contents of bioactive components? J Cereal Sci 65:236–243. https://doi.org/10.1016/j.jcs.2015.07.014
Song P, Wang H, Theodoratou E, Chan KY, Rudan I (2018) The national and subnational prevalence of cataract and cataract blindness in China: a systematic review and meta-analysis. J Glob Health 8:010804. https://doi.org/10.7189/jogh.08.010804
Study H (2007) Antioxidants and prevention of cognitive decline. Arch Intern Med 167:2167–2168. https://doi.org/10.1002/14651858.CD002854.10
Wu J, Cho E, Willett WC, Sastry SM, Schaumberg DA (2015) Intakes of lutein, zeaxanthin, and other carotenoids and age-related macular degeneration during 2 decades of prospective follow-up. JAMA Ophthalmol 133:1415–1424. https://doi.org/10.1001/jamaophthalmol.2015.3590
Zhu X, Zhang S, Chang R, Lu Y (2017) New cataract markers: mechanisms of disease. Clin Chim Acta 472:41–45. https://doi.org/10.1016/j.cca.2017.07.010
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Dror, Y., Rimon, E., Vaida, R. (2020). The Effect of the Yellow Pigments on the Ocular Functions, the Effect on the Cognition, and the Development. In: Whole-Wheat Bread for Human Health. Springer, Cham. https://doi.org/10.1007/978-3-030-39823-1_18
Download citation
DOI: https://doi.org/10.1007/978-3-030-39823-1_18
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-39822-4
Online ISBN: 978-3-030-39823-1
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)