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Toxicity Management for Central Nervous System Tumors in Radiation Oncology

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Prevention and Management of Acute and Late Toxicities in Radiation Oncology

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Abstract

Radiation therapy (RT) is used widely for the treatment of primary and metastatic brain tumors. The protection of organs at risk (OAR) in the central nervous system (CNS) is crucial, especially to preserve cognition in cancer survivors. This chapter will outline the pathophysiology of radiation-induced CNS toxicity, biologic and clinical principles of CNS tolerance to radiation, and the treatment strategies of both acute and chronic radiation-induced CNS toxicity.

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Authors and Affiliations

  1. Faculty of Medicine, Department of Radiation Oncology, Selcuk Meram University, Konya, Turkey

    Guler Yavas

  2. Hacettepe University, Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey

    Gozde Yazici

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  1. Guler Yavas
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  2. Gozde Yazici
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Correspondence to Gozde Yazici .

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Editors and Affiliations

  1. Chair and Professor, Department of Radiation Oncology, Hacettepe University, Faculty of Medicine, Ankara, Turkey

    Gokhan Ozyigit

  2. Chair and Professor, Department of Radiation Oncology, Koc University, Faculty of Medicine, Istanbul, Turkey

    Ugur Selek

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Yavas, G., Yazici, G. (2020). Toxicity Management for Central Nervous System Tumors in Radiation Oncology. In: Ozyigit, G., Selek, U. (eds) Prevention and Management of Acute and Late Toxicities in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-37798-4_1

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