Abstract
Penile cancer is a rare neoplasm, most commonly affecting men aged 50–70 years old and it representing less than 1% of all malignancies in the USA and Europe, but it represents a significant public health hazard in the developing world. The most common site for penile cancer is the glans, followed by the prepuce, or both. The vast majority of invasive neoplasms of the penis are squamous cell carcinoma. Other primary malignancies include but are not limited to basal cell carcinoma, extra-mammary Paget’s disease, melanoma, lymphoma and various rare mesenchymal tumours. There are many risk factors which may predispose to preputial malignancies; some of it are debatable; like akroposthia, buried penis, phimosis, and banalities xerotica, others are well documented like smoking and papilloma virus infection. There are many benign pathologies which are incriminated as a precancerous lesions; like Zoon’s balanitis, condyloma acuminatum and Queyrat Bowen’s disease. Also, penile and preputial neoplasia are detected infrequently in animals, specially horses and dogs and represents a diagnostic and therapeutic challenges.
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- AABP:
-
Adult acquired buried penis
- HPV:
-
Human Papilloma virus
- MALToma:
-
Mucosal-associated lymphoid tissue lymphoma
- PCB:
-
Plasma cell balanitis
- PeIN:
-
Penile intraepithelial neoplasia
- SCC:
-
Penile squamous cell carcinoma
- WHO:
-
The World Health Organisation
- ZB:
-
Zoon’s balanitis
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Fahmy, M.A.B. (2020). Preputial Malignancy. In: Normal and Abnormal Prepuce. Springer, Cham. https://doi.org/10.1007/978-3-030-37621-5_31
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DOI: https://doi.org/10.1007/978-3-030-37621-5_31
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