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Brainstem Auditory Evoked Potentials

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Clinical Evoked Potentials

Abstract

This chapter discusses brainstem auditory evoked potentials (BAEPs), its recording technique, and standard recording protocol. Major BAEP components are described in the Cz to the ipsilateral and contralateral ear derivations, emphasizing the morphological differences seen within these two derivations and the reason for these differences. Generator sources of BAEP components in the brainstem are described as revealed by direct recording from human and animal brainstems as well as clinical studies. This is followed by methods of BAEP evaluation, criteria of abnormalities, their clinical significance, and various subject-related and technical factors, which influence these responses. BAEPs provide a sensitive electrophysiological tool to evaluate integrity of brainstem in patients with coma, demyelinating disorders, posterior fossa tumors, hearing problems in infants, and during intracranial surgeries in the region of posterior fossa. These applications are fully discussed. More than 35 figures and 10 tables illustrate various BAEP characteristics and abnormalities. Included at the end of the chapter are six clinical cases discussed under the following headings, reason for study, technical summary, findings, interpretation, follow-up, and discussion, to provide a recommended method of writing BAEP reports for the referring physician.

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References

  • American Academy of Pediatrics Joint Committee on Infant Hearing. Position statement 1982. Pediatrics. 1982;70:496–7.

    Google Scholar 

  • American Clinical Neurophysiology Society, Guideline 10. Guidelines for writing clinical evoked potential reports. J Clin Neurophysiol. 2006;23:180–3.

    Article  Google Scholar 

  • American Clinical Neurophysiology Society, Guideline 9C. Guidelines on short-latency auditory evoked potentials. J Clin Neurophysiol. 2006;23:157–67.

    Article  Google Scholar 

  • Chiappa KH, Gladstone JJ, Young RR. Brainstem auditory evoked responses: studies of waveform variation in 50 normal human subjects. Arch Neurol. 1979;36:180–3.

    Article  Google Scholar 

  • Chiappa KH, Harrison JL, BrooksE B, Young RR. Brainstem auditory evoked responses in 200 patients with multiple sclerosis. Ann Neurol. 1980;7:135–43.

    Article  CAS  PubMed  Google Scholar 

  • Church MW, Williams HL. Dose and time dependent effects of ethanol in brainstem auditory evoked responses in young adult males. Electroencephalogr Clin Neurophysiol. 1982;54:161–74.

    Article  CAS  PubMed  Google Scholar 

  • Davis SL, Aminoff MJ, Berg BO. Brainstem auditory evoked potentials in children with brainstem or cerebellar dysfunction. Arch Neurol. 1985;42:156–60.

    Article  CAS  PubMed  Google Scholar 

  • Galambos R, Hicks GE, Wilson MJ. The auditory brainstem response reliably predicts hearing loss in graduates of a tertiary intensive care nursery. Ear Hear. 1984;5:254–60.

    Article  CAS  PubMed  Google Scholar 

  • Garg BP, Markand ON, Bustion PF. Brainstem auditory evoked responses in hereditary motor-sensory neuropathy: site of origin of wave II. Neurology. 1982;22:1017–9.

    Article  Google Scholar 

  • Garg BP, Markand ON, DeMyer WE, et al. Usefulness of BAEP studies in the early diagnosis of Pelizaeus-Merzbacher disease. Neurology. 1983;33:955–6.

    Article  CAS  PubMed  Google Scholar 

  • Goldie WD, Chiappa JH, Young RR, Brooks EB. Brainstem auditory and short latency somatosensory evoked responses in brain death. Neurology. 1981;31:248–56.

    Article  CAS  PubMed  Google Scholar 

  • Hari R, Sulkava R, Haltia M. Brainstem auditory evoked responses and alpha-pattern coma. Ann Neurol. 1982;11:187–9.

    Article  CAS  PubMed  Google Scholar 

  • Hashimoto I, Ishiyama YY, Nemoto S. Brainstem auditory evoked potentials recorded directly from human brainstem and thalamus. Brain. 1981;104:841–59.

    Article  CAS  PubMed  Google Scholar 

  • Hecox KE, Cone B. Prognostic importance of brainstem auditory evoked responses after asphyxia. Neurology (NY). 1981;31:1429–33.

    Article  CAS  Google Scholar 

  • Krumholz A, Felix JK, Goldstein PJ, et al. Maturation of the brainstem auditory evoked potential in premature infants. Electroencephalogr Clin Neurophysiol. 1985;62:124–34.

    Article  CAS  PubMed  Google Scholar 

  • Legatt AD. Mechanism of intraoperative brainstem auditory evoked potential change. J Clin Neurophysiol. 2002;19:396–408.

    Article  PubMed  Google Scholar 

  • Legatt AD, Pedley TA, Emerson RG, et al. Normal brain-stem auditory evoked potentials with abnormal latency- intensity studies in patients with acoustic neuromas. Arch Neurol. 1988;45:1326–30.

    Article  CAS  PubMed  Google Scholar 

  • Markand ON. Brainstem auditory evoked potentials. J Clin Neurophysiol. 1994;11:319–42.

    Article  CAS  PubMed  Google Scholar 

  • Markand ON, Garg BP, DeMyer WE, et al. Brainstem auditory, visual and somatosensory evoked potentials in leukodystrophies. Electroencephalogr Clin Neurophysiol. 1982;54:39–48.

    Article  CAS  PubMed  Google Scholar 

  • Markand ON, Lee BI, Warren C, et al. Effects of hypothermia on brainstem auditory evoked potentials in humans. Ann Neurol. 1987;22:507–13.

    Article  CAS  PubMed  Google Scholar 

  • Markand ON, Farlow MR, Stevens JC, Edwards MK. Brain stem auditory potential abnormalities with unilateral brainstem lesions demonstrated by magnetic resonance imaging. Arch Neurol. 1989;46:295–9.

    Article  CAS  PubMed  Google Scholar 

  • Maurer K, Strumpel D, Wende S. Acoustic tumor detection with early auditory evoked potentials and neuroradiological methods. J Neurol. 1982;227:177–85.

    Article  CAS  PubMed  Google Scholar 

  • Moller AR, Jannetta PJ. Monitoring techniques for microvascular decompression procedures. In: Loftus CM, Traynelis VC, editors. Intraoperative monitoring techniques in neurosurgery. New York: McGraw-Hill, Inc.; 1994. p. 163–74.

    Google Scholar 

  • Moller AG, Jannetta P, Bennett M, Moller MB. Intracranially recorded responses from the human auditory nerve: new insights into the origin of brainstem evoked potentials (BAEPs). Electroencephalogr Clin Neurophysiol. 1981;52:18–27.

    Article  CAS  PubMed  Google Scholar 

  • Nina Kraus, Özcan Özdamar, Peter T Heydemann, Laszlo Stein, Nancy L Reed. Auditory brain-stem responses in hydrocephalic patients. Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section. 1984;59(4):310–7.

    Article  CAS  Google Scholar 

  • Ochs R, Markand ON, DeMyer WE. Brainstem auditory evoked responses in leukodystrophies. Neurology. 1979;29:1089–93.

    Article  CAS  PubMed  Google Scholar 

  • Oh SJ, Kuba T, Soyer A, Choi S, Bonikowski FP, Vitek J. Lateralization of brainstem lesions by brainstem auditory evoked potentials. Neurology (NY). 1981;31:14–8.

    Article  CAS  Google Scholar 

  • Pedersen L, Trojaborg W. Visual, auditory and somatosensory pathway involvement in hereditary cerebellar ataxia, Friedreich’s ataxia and familial spastic paraplegia. Electroencephalogr Clin Neurophysiol. 1981;52:283–97.

    Article  CAS  PubMed  Google Scholar 

  • Picton TW, Durieux-Smith A. Auditory evoked potentials in the assessment of hearing. Neurol Clin. 1988;6:791–808.

    Article  CAS  PubMed  Google Scholar 

  • Prasher D, Sainz M, Gibson WPR. Binaural voltage summation of brainstem auditory evoked potentials: an adjunct to the diagnostic criteria for multiple sclerosis. Ann Neurol. 1982;11:86–91.

    Article  CAS  PubMed  Google Scholar 

  • Radtke RA, Erwin CW, Wilkins RH. Intraoperative brainstem auditory evoked potentials: significant decrease in postoperative morbidity. Neurology. 1989;39:187–91.

    Article  CAS  PubMed  Google Scholar 

  • Robinson K, Rudge P. Abnormalities of the auditory evoked potentials in patients with multiple sclerosis. Brain. 1977;100:19–40.

    Article  PubMed  Google Scholar 

  • Robinson K, Rudge P. The use of the auditory evoked potential in the diagnosis of multiple sclerosis. J Neurol Sci. 1980;45:235–44.

    Article  CAS  PubMed  Google Scholar 

  • Robinson K, Rudge P. The differential diagnosis of cerebellopontine angle lesions. Multidisciplinary approach with special emphasis on the brainstem auditory evoked potential. J Neurol Sci. 1983;60:1–21.

    Article  CAS  PubMed  Google Scholar 

  • Ropper AM, Miett T, Chiappa KH. Absence of evoked potential abnormalities in acute transverse myelopathy. Neurology. 1982;32:80–2.

    Article  CAS  PubMed  Google Scholar 

  • Rossini PM, Cracco JB. Somatosensory and brainstem auditory evoked potentials in neurodegenerative system disorders. Eur Neurol. 1987;26:176–88.

    Article  CAS  PubMed  Google Scholar 

  • Salamy A. Maturation of auditory brainstem response from birth to early childhood. J Clin Neurophysiol. 1984;1:293–329.

    Article  CAS  PubMed  Google Scholar 

  • Sloan TB. Anesthetic effect on electrophysiological recordings. J Clin Neurophysiol. 1998;15:217–26.

    Article  CAS  PubMed  Google Scholar 

  • Starr A. Auditory brainstem responses in brain death. Brain. 1976;99:543–54.

    Article  CAS  PubMed  Google Scholar 

  • Starr A, Squires K. Distribution of auditory brainstem potentials over the scalp and nasopharynx in humans. Ann N Y Acad Sci. 1982;388:427–42.

    Article  CAS  PubMed  Google Scholar 

  • Stockard JJ, Rossiter VS. Clinical and pathologic correlates of brainstem auditory response abnormalities. Neurology. 1977;27:316–25.

    Article  CAS  PubMed  Google Scholar 

  • Stockard JJ, Sharbrough FW. Unique contributions of short latency sensory evoked potentials to neurologic diagnosis. Prog Clin Neurophysiol. 1980;7:231–63.

    Google Scholar 

  • Stockard JE, Westmoreland BF. Technical considerations in the recording and interpretation of the brainstem auditory potentials for neonatal neurological diagnosis. Am J EEG Technol. 1981;21:31.

    Article  Google Scholar 

  • Stockard JJ, Rossiter VS, Jones TA, Sharbrough FW. Effects of centrally acting drug on brainstem auditory responses. Electroencephalogr Clin Neurophysiol. 1977;43:550–1.

    Google Scholar 

  • Stockard JJ, Sharbrough FW, Tinker JA. Effects of hypothermia on the human brainstem auditory response. Ann Neurol. 1978a;3:368–70.

    Article  CAS  PubMed  Google Scholar 

  • Stockard JJ, Stockard JE, Sharbrough FW. Nonpathologic factors influencing brainstem auditory evoked potentials. Am J EEG Technol. 1978b;18:177–209.

    Article  Google Scholar 

  • Stockard JE, Stockard JJ, Westmoreland BF, Corfits JL. Brainstem auditory-evoked responses: Normal variation as a function of stimulus and subject characteristics. Arch Neurol. 1979;36:823–31.

    Article  CAS  PubMed  Google Scholar 

  • Stockard JE, Stockard JJ, Kleinberg F, Westmoreland BF. Prognostic value of brainstem auditory evoked potentials in neonates. Arch Neurol. 1983;40:360–5.

    Article  CAS  PubMed  Google Scholar 

  • Taylor MJ, Houston BD, Lowry NJ. Recovery of auditory brainstem responses in severe hypoxic-ischemic insult. N Engl J Med. 1983;309:1169–70.

    Article  CAS  PubMed  Google Scholar 

  • Thivierge J, Cote R. Brainstem auditory evoked responses (BAER): normative study in children and adults. Electroencephalogr Clin Neurophysiol. 1987;68:479–84.

    Article  CAS  PubMed  Google Scholar 

  • Tsubokawa T, Nishimoto H, Yamamoto T, Kitamura M, Katayrna Y, Moriyasu N. Assessment of brainstem damage by the auditory brainstem responses in acute severe head injury. J Neurol Neurosurg Psychiatry. 1980;43:1005–11.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Warren MP. The auditory brain stem responses in pediatrics. Otolaryng Clin North Am. 1989;22:473–500.

    CAS  Google Scholar 

  • Worley G, Erwin CW, Schuster JM, et al. BAEPs in infants with myelomeningocele and later development of Chiari II malformation related brainstem dysfunction. Dev Med Child Neurol. 1994;36:707–15.

    Article  CAS  PubMed  Google Scholar 

  • Wrege K, Starr A. Binaural interaction in human auditory brainstem evoked potentials. Arch Neurol. 1981;38:572–80.

    Article  CAS  PubMed  Google Scholar 

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Markand, O.N. (2020). Brainstem Auditory Evoked Potentials. In: Clinical Evoked Potentials. Springer, Cham. https://doi.org/10.1007/978-3-030-36955-2_2

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  • DOI: https://doi.org/10.1007/978-3-030-36955-2_2

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